Target Detail

Papain-like proteinase

Abbreviation: PLP/Plpro
State: Trimer

Uniprot id / Protein id:QHD43415.1

Organism:SARS-CoV-2

Mechanism:PLP is responsible for the cleavage of non-structural proteins (nsp) 1, 2 and 3. In addition, PLP can deubiquitinate or deISGylate host cell proteins, resulting in the immune suppression of host cells.

Reference (PMID or DOI):20181693, 19369340

Model Source:PDB

Template PDB_ID:6w9c

Pockets:There are 18 pockets in Papain-like proteinase.
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