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CoViProteins
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2019-nCoV
Target Detail
Papain-like proteinase
Abbreviation: PLP/Plpro
State: Trimer
Uniprot id / Protein id:
QHD43415.1
Organism:
SARS-CoV-2
Mechanism:
PLP is responsible for the cleavage of non-structural proteins (nsp) 1, 2 and 3. In addition, PLP can deubiquitinate or deISGylate host cell proteins, resulting in the immune suppression of host cells.
Reference (PMID or DOI):
20181693
,
19369340
Model Source:
PDB
Template PDB_ID:
6w9c
Pockets:
There are 18 pockets in Papain-like proteinase.
pocket 1:
pocket 2:
pocket 3:
pocket 4:
pocket 5:
pocket 6:
pocket 7:
pocket 8:
pocket 9:
pocket 10:
pocket 11:
pocket 12:
pocket 13:
pocket 14:
pocket 15:
pocket 16:
pocket 17:
pocket 18:
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