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CoViProteins
2019-nCoV
CoViLigands
Introduction
2019-nCoV
Target Detail
Citrate lyase subunit beta-like protein, mitochondrial
Abbreviation: CLYBL
Uniprot id / Protein id:
Q8N0X4
Organism:
human
Mechanism:
CLYBL converts the immune modulatory TCA cycle metabolite itaconate through the citramalyl-CoA intermediate to acetyl-CoA, an increase in CLYBL may lead to the depletion of itaconate, limiting its anti-inflammatory function
Reference (PMID or DOI):
35290573
Model Source:
PDB
Template PDB_ID:
5vxc
Pockets:
There are 5 pockets in Citrate lyase subunit beta-like protein, mitochondrial.
pocket 1:
pocket 2:
pocket 3:
pocket 4:
pocket 5:
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