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CoViProteins
2019-nCoV
CoViLigands
Introduction
2019-nCoV
Target Detail
ORF1ab polyprotein 6799-7096 2'-O-methyltransferase
Abbreviation: 2'-O-Mtase
Uniprot id / Protein id:
QHD43415.1
Organism:
SARS-CoV-2
Mechanism:
2'-O-Mtase can mediate mRNA cap 2'-O-ribose methylation to the 5'-cap structure of viral mRNAs which is essential to evade immune system.
Reference (PMID or DOI):
21637813
,
18417574
Model Source:
Swiss-model
Template PDB_ID:
2xyr
Sequence Identity:
93.49%
Pockets:
There are 5 pockets in ORF1ab polyprotein 6799-7096 2'-O-methyltransferase.
pocket 1:
pocket 2:
pocket 3:
pocket 4:
pocket 5:
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