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2019-nCoV
Target Detail
cGMP-specific 3',5'-cyclic phosphodiesterase
Abbreviation: PDE5
Uniprot id / Protein id:
O76074
Organism:
human
Mechanism:
PDEs is responsible for the degradation of cAMP, which may aggravate the virus-induced pulmonary fibrosis.
Reference (PMID or DOI):
10.1101/2020.02.27.20027557
Model Source:
PDB
Template PDB_ID:
2h44
Pockets:
There are 10 pockets in cGMP-specific 3',5'-cyclic phosphodiesterase.
pocket 1:
pocket 2:
pocket 3:
pocket 4:
pocket 5:
pocket 6:
pocket 7:
pocket 8:
pocket 9:
pocket 10:
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