D3Targets-2019-nCoV

D3Docking

D3Similarity

D3AI-CoV

D3Pockets

D3AI-Spike

CoViProteins

2019-nCoV

CoViLigands

Mol ID	CAS	Target Name	Target ID	Activity	Remarks	References	Crystal Structure
ICV1(covalent)	958634-20-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10µM)	Anti-SARS-CoV	17855091/26592814	4ZRO
ICV2(covalent)	1803562-02-8	virus: 3C-like protease	P0DTD1	FIPV 3CL(IC50=1.3µM)	Anti-FIPV	26592814
ICV3(covalent)	958634-22-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=15µM)	Anti-SARS-CoV	17855091
ICV4(covalent)	860400-08-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=45µM)	Anti-SARS-CoV	16250632
ICV5(covalent)	2229818-46-4	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=2.4µM); SARS 3CL(IC50=0.7µM)	Anti-MERS-CoV/SARS-CoV	28216367
ICV6(covalent)	1065478-45-6	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=4.7µM); SARS 3CL(IC50=0.5µM)	Anti-MERS-CoV/SARS-CoV	28216367
ICV7(covalent)	1065478-52-5	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=1.7µM); SARS 3CL(IC50=0.2µM)	Anti-MERS-CoV/SARS-CoV	28216367
ICV8	1650544-15-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=108µM)	Anti-SARS-CoV	25614110	4TWY
ICV9	1650544-57-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=68µM)	Anti-SARS-CoV	25614110
ICV10	1650544-16-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=63µM)	Anti-SARS-CoV	25614110	4TWW
ICV11	1650544-45-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=240µM)	Anti-SARS-CoV	25614110	4WY3
ICV12	1650544-48-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=175µM)	Anti-SARS-CoV	25614110
ICV13	1650544-51-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=135µM)	Anti-SARS-CoV	25614110
ICV14	1650544-54-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=135µM)	Anti-SARS-CoV	25614110
ICV15	1650544-59-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=57µM)	Anti-SARS-CoV	25614110
ICV16	1329045-25-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=30µM)	Anti-SARS-CoV	26879854
ICV17	1883280-28-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=65µM)	Anti-SARS-CoV	26879854
ICV18	2097058-27-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=43µM)	Anti-SARS-CoV	28454669
ICV19	192725-17-0	virus: 3C-like protease	P0DTD1	MERS(EC50=11.6µM) Cal-3	Anti-MERS-CoV	31924756
ICV20	155213-67-5	virus: 3C-like protease	P0DTD1	MERS(EC50=24.9µM) Calu-3	Anti-MERS-CoV	31924756
ICV21(covalent)	1416992-39-6	virus: 3C-like protease	P0DTD1	SARS recombinant 3CL or 3CL(IC50=4.35µM); SARS-CoV-2 3CL(IC50=0.03µM)	Anti-SARS-CoV/SARS-CoV-2	22915796/32541865/32855413	"3UR9, 4DCD, 4F49, 5WKJ, 6WTT, 6WTJ"
ICV22	1333231-50-7	virus: 3C-like protease	P0DTD1	SARS recombinant 3CL or 3CL(IC50=4.66µM)	Anti-SARS-CoV	22915796
ICV23(covalent)	1333231-44-9	virus: 3C-like protease	P0DTD1	SARS recombinant 3CL or 3CL(IC50=3.48µM); SARS-CoV-2 3CL(IC50=0.4µM)	Anti-SARS-CoV/SARS-CoV-2	22915796/32855413	6WTK
ICV24(covalent)	2170616-59-6	virus: 3C-like protease	P0DTD1	MERS(EC50=0.5µM)	Anti-MERS-CoV	29544147	5WKK
ICV25	1945974-07-1	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=7.4µM); SARS 3CL(IC50=5.8µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV26	1945974-06-0	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=7.3µM); SARS 3CL(IC50=6.0µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV27	1945974-10-6	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=30.3µM); SARS 3CL(IC50=41.2µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV28	1945974-03-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=44.7µM)	Anti-SARS-CoV	27240464
ICV29	1945974-04-8	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=12.2µM); SARS 3CL(IC50=16.4µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV30	1945974-05-9	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=10.1µM); SARS 3CL(IC50=20.2µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV31	1945974-12-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=37.5µM)	Anti-SARS-CoV	27240464
ICV32	1945974-13-9	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=8.9µM); SARS 3CL(IC50=11.7µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV33	1945974-14-0	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=7.7µM); SARS 3CL(IC50=8.6µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV34	1945974-15-1	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=9.6µM); SARS 3CL(IC50=18.7µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV35	1945974-16-2	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=8.9µM); SARS 3CL(IC50=30.7µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV36	1945974-18-4	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=6.7µM); SARS 3CL(IC50=10.9µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV37	1945974-19-5	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=15.7µM); SARS 3CL(IC50=9.7µM)	Anti-SARS-CoV/Anti-MERS-CoV	27240464
ICV38(covalent)	2170616-51-8	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.7µM); SARS 3CL(IC50=6.3µM);FIPV 3CL(IC50=2.1µM)	Anti-SARS-CoV/Anti-MERS-CoV/Anti-FIPV	29544147	5WKL
ICV39(covalent)	2170616-55-2	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.4µM); SARS 3CL(IC50=5.1µM); FIPV 3CL(IC50=2.4µM)	Anti-SARS-CoV/Anti-MERS-CoV/Anti-FIPV	29544147
ICV40(covalent)	2227525-76-8	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.6µM); SARS 3CL(IC50=2.1µM); FIPV(IC50=0.8µM)	Anti-SARS-CoV/Anti-MERS-CoV/Anti-FIPV	29544147
ICV41(covalent)	2227525-78-0	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.8µM); SARS 3CL(IC50=5.2µM); FIPV 3CL(IC50=1.6µM)	Anti-SARS-CoV/Anti-MERS-CoV/Anti-FIPV	29544147
ICV42(covalent)	2227525-79-1	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.7µM); SARS 3CL(IC50=3.9µM); FIPV 3CL(IC50=0.8µM)	Anti-SARS-CoV/Anti-MERS-CoV/Anti-FIPV	29544147
ICV43	2303978-66-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.47µM)	Anti-SARS-CoV	30784880
ICV44	2303978-65-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=3.3µM)	Anti-SARS-CoV	30784880
ICV45	2303978-68-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.54µM)	Anti-SARS-CoV	30784880
ICV46	2993-5-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13.9µM)	Anti-MSARS-CoV	24332657
ICV47	223537-30-2	virus: 3C-like protease	P0DTD1	HCoV-EMC 3CL(IC50=0.28µM)	Anti-HCoV-EMC	23549610
ICV48	860400-11-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=80µM)	Anti-SARS-CoV	15994085
ICV49	223526-09-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=85µM)	Anti-SARS-CoV	15994085
ICV50	860400-13-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=31µM)	Anti-SARS-CoV	15994085
ICV51	860400-14-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13µM)	Anti-SARS-CoV	15994085
ICV52	860400-15-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=38µM)	Anti-SARS-CoV	15994085
ICV53	860400-17-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=11µM)	Anti-SARS-CoV	15994085
ICV54	860400-18-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=30µM)	Anti-SARS-CoV	15994085
ICV55	860400-19-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=11µM)	Anti-SARS-CoV	15994085
ICV56	862415-05-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5µM); SARS(ec50=9.45µM) Vero E6	Anti-SARS-CoV	15994085
ICV57	862415-07-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=1µM); SARS(ec50=0.18µM) Vero E6	Anti-SARS-CoV	15994085
ICV58	862415-09-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10µM); SARS(ec50=0.11µM) Vero E6	Anti-SARS-CoV	15994085
ICV59	862415-11-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=7µM); SARS(ec50=0.16µM) Vero E6	Anti-SARS-CoV	15994085
ICV61	761416-68-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=40µM)	Anti-SARS-CoV	15226499
ICV62	761416-69-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=25µM)	Anti-SARS-CoV	15226499
ICV63	761416-70-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=35µM)	Anti-SARS-CoV	15226499
ICV64	761416-71-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=24µM)	Anti-SARS-CoV	15226499
ICV65	761416-73-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=25µM)	Anti-SARS-CoV	15226499
ICV66	761416-74-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=24µM)	Anti-SARS-CoV	15226499
ICV67	761416-75-5	virus: 3C-like protease	P0DTD1	SARS(EC50=0.6µM) Vero	Anti-SARS-CoV	15226499
ICV68	1166-34-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.92µM); HCoV-229E 3CL(IC50=4.68µM)	Anti-SARS-CoV/HCoV-229E	15890949
ICV69(covalent)	856242-63-2	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.053µM); HCoV-229E 3CL(Ki=0.068µM); HCoV-229E(IC50=0.14µM) MRC-5;SARS(IC50=0.6µM) Vero E6	Anti-SARS-CoV	16884309	7C8T
ICV70(covalent)	869494-29-1	virus: 3C-like protease	P0DTD1	SARS 3CL(Kinact=0.045/min)	Anti-SARS-CoV	16250632	2ALV
ICV71(covalent)	869494-44-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Kinact=0.0025/min)	Anti-SARS-CoV	16250632
ICV72	313244-76-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.5µM)	Anti-SARS-CoV	15380189
ICV73	1086304-31-5	virus: 3C-like protease	P0DTD1	Replicon (BHK) (IC50=2µM); SARS(IC50=8.9µM) Vero	Anti-SARS-CoV	18584889
ICV74	2390446-22-5	virus: 3C-like protease	P0DTD1	SARS 3CL (IC50=26µM)	Anti-SARS-CoV	30558861
ICV75	2390446-17-8	virus: 3C-like protease	P0DTD1	SARS 3CL (IC50=175µM)	Anti-SARS-CoV	30558861
ICV76	860400-16-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=21µM)	Anti-SARS-CoV	15994085
ICV77	862415-03-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10µM); SARS(EC50=6.44µM) Vero E6	Anti-SARS-CoV	15994085
ICV78	860400-12-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=39µM)	Anti-SARS-CoV	15994085
ICV79	898264-58-9	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.66µM); HCoV-229E(IC50=9.1µM) MRC-5	Anti-SARS-CoV	16884309
ICV80	898264-59-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.058µM); HCoV-229E(IC50=0.88µM) MRC-5	Anti-SARS-CoV	16884309
ICV81	813451-42-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=3.4µM)	Anti-SARS-CoV	26878082/15566280
ICV82	813451-41-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.6µM)	Anti-SARS-CoV	26878082/15566280
ICV83	813451-40-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.7µM)	Anti-SARS-CoV	26878082/15566280
ICV84	813451-39-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.9µM)	Anti-SARS-CoV	26878082/15566280
ICV85	813451-38-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=53µM)	Anti-SARS-CoV	26878082/15566280
ICV86	813451-36-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=64µM)	Anti-SARS-CoV	26878082/15566280
ICV87	813451-35-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=28µM)	Anti-SARS-CoV	26878082/15566280
ICV88	860399-70-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.06µM)	Anti-SARS-CoV	26878082/15974598
ICV89	860399-72-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2µM)	Anti-SARS-CoV	15974598
ICV90	860399-71-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=3µM)	Anti-SARS-CoV	15974598
ICV91	860399-75-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=7µM)	Anti-SARS-CoV	15974598
ICV92	860399-76-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4µM)	Anti-SARS-CoV	15974598
ICV93	860399-78-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=19µM)	Anti-SARS-CoV	15974598
ICV94	860399-79-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5µM)	Anti-SARS-CoV	15974598
ICV95	860399-81-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5µM)	Anti-SARS-CoV	15974598
ICV96	1345826-14-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.39µM)	Anti-SARS-CoV	22014094
ICV97	1271932-54-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5.7µM)	Anti-SARS-CoV	22014094	3AW0
ICV98	1345826-16-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.27µM)	Anti-SARS-CoV	22014094
ICV99	1345826-17-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10µM)	Anti-SARS-CoV	22014094
ICV100	1345826-18-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.34µM)	Anti-SARS-CoV	22014094
ICV101	1345826-19-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.098µM)	Anti-SARS-CoV	22014094	3ATW
ICV102	1345826-15-4	virus: 3C-like protease	P0DTD1	SARS 3CL (IC50=65µM)	Anti-SARS-CoV	26878082/22014094	3AVZ
ICV103	1092982-23-4	virus: 3C-like protease	P0DTD1	SARS 3CL R188I mutant protease(IC50=37µM)	Anti-SARS-CoV	26878082/18845442
ICV104	1163302-21-3	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=21µM)	Anti-SARS-CoV	26878082
ICV105	1163302-39-3	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=2.2µM)	Anti-SARS-CoV	26878082
ICV106	1471484-62-4	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.0063µM)	Anti-SARS-CoV	26878082/23994330
ICV107	1417704-35-8	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.0031µM)	Anti-SARS-CoV	26878082/23994330
ICV108	1471484-34-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=2.7µM)	Anti-SARS-CoV	26878082/23994330
ICV109	1471484-50-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=1.7µM)	Anti-SARS-CoV	26878082/23994330
ICV110	1471484-52-2	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.065µM)	Anti-SARS-CoV	26878082/23994330
ICV111	1471484-54-4	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.067µM)	Anti-SARS-CoV	26878082/23994330
ICV112	1471484-56-6	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.16µM)	Anti-SARS-CoV	26878082/23994330
ICV113	1471484-58-8	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.028µM)	Anti-SARS-CoV	26878082/23994330
ICV114	1471484-60-2	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.33µM)	Anti-SARS-CoV	26878082/23994330
ICV115	1471484-64-6	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.048µM)	Anti-SARS-CoV	26878082/23994330
ICV116	1471484-66-8	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.03µM)	Anti-SARS-CoV	26878082/23994330
ICV117	1471484-68-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.026µM)	Anti-SARS-CoV	26878082/23994330
ICV118	1471484-70-4	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=6.7µM)	Anti-SARS-CoV	26878082/23994330
ICV119	1471484-72-6	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=7.5µM)	Anti-SARS-CoV	26878082/23994330
ICV120	1471484-74-8	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.022µM)	Anti-SARS-CoV	26878082/23994330
ICV121	1471484-76-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.8µM)	Anti-SARS-CoV	26878082/23994330
ICV122	1471484-78-2	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.12µM)	Anti-SARS-CoV	26878082/23994330
ICV123	1471484-80-6	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=14µM)	Anti-SARS-CoV	26878082/23994330
ICV124	1471484-82-8	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=0.68µM)	Anti-SARS-CoV	26878082/23994330
ICV125(covalent)	1034140-76-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=15µM)	Anti-SARS-CoV	26878082/18329272
ICV126(covalent)	191981-66-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=20µM)	Anti-SARS-CoV	26878082/18329272
ICV127(covalent)	1034140-77-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=40µM)	Anti-SARS-CoV	26878082/18329272
ICV128(covalent)	1034140-83-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10µM)	Anti-SARS-CoV	26878082/18329272
ICV129	865372-07-2	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=45.8µM)	Anti-SARS-CoV	26878082/16250642
ICV130	868074-90-2	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=35.3µM)	Anti-SARS-CoV	26878082/16250642
ICV131	861216-05-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.82µM)	Anti-SARS-CoV	26878082/15896959
ICV132	861216-02-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.98µM)	Anti-SARS-CoV	26878082/15896959
ICV133	861215-94-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2µM)	Anti-SARS-CoV	26878082/15896959
ICV134	861215-87-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=7.2µM)	Anti-SARS-CoV	26878082/15896959
ICV135	861216-06-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.95µM)	Anti-SARS-CoV	26878082/15896959
ICV136	1529815-11-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=1.04µM)	Anti-SARS-CoV	26878082/24316352
ICV137	1529814-98-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=82.91µM)	Anti-SARS-CoV	24316352
ICV138	1529815-04-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13.86µM)	Anti-SARS-CoV	24316352
ICV139	1446515-15-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5.52µM)	Anti-SARS-CoV	24316352
ICV140	1529815-09-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=14µM)	Anti-SARS-CoV	24316352
ICV141	1529815-10-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=39.87µM)	Anti-SARS-CoV	24316352
ICV142	1529815-12-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=1.69µM)	Anti-SARS-CoV	24316352
ICV143	1529815-15-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.7µM)	Anti-SARS-CoV	24316352
ICV144	482-35-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=42.79µM)	Anti-SARS-CoV	26878082/17046271
ICV145	482-36-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=24.14µM)	Anti-SARS-CoV	26878082/17046271
ICV146	481-46-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=32µM)	Anti-SARS-CoV	26878082/20934345
ICV147	521-34-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=38.4µM)	Anti-SARS-CoV	26878082/20934345
ICV148	521-32-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=72.3µM)	Anti-SARS-CoV	26878082/20934345
ICV149	34157-83-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10.3µM)	Anti-SARS-CoV	26878082/20167482
ICV150	1258-84-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5.5µM)	Anti-SARS-CoV	26878082/20167482
ICV151	50802-21-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=9.9µM)	Anti-SARS-CoV	26878082/20167482
ICV152	53527-47-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.6µM)	Anti-SARS-CoV	26878082/20167482
ICV153	472-15-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10µM)	Anti-SARS-CoV	26878082/17663539
ICV154	493-95-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=25µM)	Anti-SARS-CoV	26878082/17663539
ICV155	246020-69-9	virus: 3C-like protease	P0DTD1	SARS 3CL(58% inhibition at 10µM)	Anti-SARS-CoV	26878082/16913704
ICV156	882289-58-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=11µM)	Anti-SARS-CoV	26878082/16759091
ICV157	882289-60-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=12µM)	Anti-SARS-CoV	26878082/16759091
ICV158	1257976-18-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=6.8µM)	Anti-SARS-CoV	26878082/20947359
ICV159	1257976-20-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=8.4µM)	Anti-SARS-CoV	26878082/20947359
ICV160	1257976-10-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5.5µM)	Anti-SARS-CoV	26878082/20947359
ICV161	1203458-14-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10.6µM)	Anti-SARS-CoV	26878082/20494577
ICV162	1203458-15-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=6.1µM)	Anti-SARS-CoV	26878082/20494577
ICV164	70-30-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=5µM)	Anti-SARS-CoV	19275708/15950190
ICV166	50-56-6	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=2.2µM); SARS(EC50=12µM) Vero E6	Anti-SARS-CoV	19275708
ICV167	1428-95-1	virus: 3C-like protease	P0DTD1	HCoV-229E(EC50=1.34µM) MRC5	Anti-HCoV-229E	19275708
ICV168	890402-73-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=17.4µM)	Anti-SARS-CoV	26878082/16638531
ICV169	890402-75-2	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=11.1µM)	Anti-SARS-CoV	26878082/16638531
ICV170	890402-76-3	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=22.9µM)	Anti-SARS-CoV	26878082/16638531
ICV171	890402-78-5	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=12.3µM)	Anti-SARS-CoV	26878082/16638531
ICV172	88744-37-0	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=19.5µM)	Anti-SARS-CoV	26878082/16638531
ICV173	890402-77-4	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=7.5µM)	Anti-SARS-CoV	26878082/16638531
ICV174	890402-74-1	virus: 3C-like protease	P0DTD1	SARS 3CL(Ki=12.1µM)	Anti-SARS-CoV	26878082/16638531
ICV175	1026559-41-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.03µM)	Anti-SARS-CoV	26878082/18796354
ICV176	1087243-18-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.31µM)	Anti-SARS-CoV	26878082/18796354
ICV177	130-17-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.3µM)	Anti-SARS-CoV	15489171
ICV178	219929-01-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.5µM)	Anti-SARS-CoV	15489171
ICV179	846012-39-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=7µM)	Anti-SARS-CoV	15489171
ICV180	27052-52-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.6µM)	Anti-SARS-CoV	15489171
ICV181	846012-42-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=7µM)	Anti-SARS-CoV	15489171
ICV182	761416-77-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=40µM)	Anti-SARS-CoV	15226499
ICV183	761416-67-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=25µM)	Anti-SARS-CoV	15226499
ICV184	761416-76-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=25µM)	Anti-SARS-CoV	15226499
ICV185	761416-72-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=23µM)	Anti-SARS-CoV	15226499
ICV186	384369-45-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=38.57µM)	Anti-SARS-CoV	21470860
ICV187	1417700-13-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=1.5µM)	Anti-SARS-CoV	23231439	3V3M
ICV188	1349571-70-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13µM)	Anti-SARS-CoV	18295820
ICV189	1087243-14-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.03µM)	Anti-SARS-CoV	18796354
ICV190	861215-88-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=9.4µM)	Anti-SARS-CoV	26878082/15896959
ICV191	861215-89-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13.5µM)	Anti-SARS-CoV	15896959
ICV192	861215-93-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13.11µM)	Anti-SARS-CoV	15896959
ICV193	861216-07-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=11.2µM)	Anti-SARS-CoV	15896959
ICV194	861216-09-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=23.5µM)	Anti-SARS-CoV	15896959
ICV195	861216-12-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=12.57µM)	Anti-SARS-CoV	15896959
ICV196	861216-17-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=17.5µM)	Anti-SARS-CoV	15896959
ICV197	489464-52-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=18.2µM)	Anti-SARS-CoV	24332657
ICV198	1310414-78-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=58.35µM)	Anti-SARS-CoV	21470860
ICV199	433325-53-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=62.79µM)	Anti-SARS-CoV	21470860
ICV200	627817-88-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=101.38µM)	Anti-SARS-CoV	21470860
ICV201	327031-17-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=77.09µM)	Anti-SARS-CoV	21470860
ICV202	488811-68-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=90.72µM)	Anti-SARS-CoV	21470860
ICV203	324566-35-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=41.39µM)	Anti-SARS-CoV	21470860
ICV204	601504-81-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=18.2µM)	Anti-SARS-CoV	18343121
ICV205	516462-89-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=17.2µM)	Anti-SARS-CoV	18343121
ICV206	371946-68-8	virus: 3C-like protease	P0DTD1	SARS 3CL(EC50=23µM)	Anti-SARS-CoV	26878082
ICV219	1473419-35-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=9.1µM)	Anti-SARS-CoV	24080461
ICV220	1473419-40-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=26µM)	Anti-SARS-CoV	24080461
ICV221	1473419-36-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=3.8µM)	Anti-SARS-CoV	24080461
ICV222	1473419-34-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=22.5µM)	Anti-SARS-CoV	24080461
ICV223	1473419-33-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.1µM)	Anti-SARS-CoV	24080461
ICV224	1473419-32-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=6.9µM)	Anti-SARS-CoV	24080461
ICV225	1473419-31-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=25.3µM)	Anti-SARS-CoV	24080461
ICV226	1473419-30-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=7.72µM)	Anti-SARS-CoV	24080461
ICV227	1473419-60-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=12.5µM)	Anti-SARS-CoV	24080461
ICV228	1473419-59-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2µM)	Anti-SARS-CoV	24080461
ICV229	1473419-58-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.7µM)	Anti-SARS-CoV	24080461
ICV230	1473419-57-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.97µM)	Anti-SARS-CoV	24080461
ICV231	1473419-56-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=0.051µM)	Anti-SARS-CoV	24080461
ICV232	1473419-55-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=1.5µM)	Anti-SARS-CoV	24080461
ICV233	1473419-54-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.1µM)	Anti-SARS-CoV	24080461
ICV234	1473419-53-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10.3µM)	Anti-SARS-CoV	24080461
ICV235	1473419-51-0	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=22.1µM)	Anti-SARS-CoV	24080461
ICV236	1473419-50-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=8.1µM)	Anti-SARS-CoV	24080461
ICV237	1473419-49-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.1µM)	Anti-SARS-CoV	24080461
ICV238	1473419-48-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=3.4µM)	Anti-SARS-CoV	24080461
ICV239	1473419-47-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13.3µM)	Anti-SARS-CoV	24080461
ICV240	87-48-9	virus: 3C-like protease	P0DTD1	90.54% inhibition ratio at 1mM	Anti-SARS-CoV	24316352
ICV241	20780-76-1	virus: 3C-like protease	P0DTD1	86.73% inhibition ratio at 1mM	Anti-SARS-CoV	24316352
ICV242	17630-76-1	virus: 3C-like protease	P0DTD1	84.17% inhibition ratio at 1mM	Anti-SARS-CoV	24316352
ICV243	443-69-6	virus: 3C-like protease	P0DTD1	82.55% inhibition ratio at 1mM	Anti-SARS-CoV	24316352
ICV244	611-09-6	virus: 3C-like protease	P0DTD1	93.96% inhibition ratio at 1mM	Anti-SARS-CoV	24316352
ICV245	39755-95-8	virus: 3C-like protease	P0DTD1	95.32% inhibition ratio at 1mM	Anti-SARS-CoV	24316352
ICV246	405508-56-7	virus: 3C-like protease	P0DTD1	95.37% inhibition ratio at 1mM	Anti-SARS-CoV	24316352
ICV247	1446515-17-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=76.74µM)	Anti-SARS-CoV	24316352
ICV248	1529814-92-3	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=31.71µM)	Anti-SARS-CoV	24316352
ICV249	1529814-93-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=32.08µM)	Anti-SARS-CoV	24316352
ICV250	1529814-94-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=34.91µM)	Anti-SARS-CoV	24316352
ICV251	1529814-95-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=10.07µM)	Anti-SARS-CoV	24316352
ICV252	1446515-16-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=51.33µM)	Anti-SARS-CoV	24316352
ICV253	329905-79-5	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.45µM)	Anti-SARS-CoV	24316352
ICV254	220510-03-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=12.66µM)	Anti-SARS-CoV	24316352
ICV255	452088-38-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=1.18µM)	Anti-SARS-CoV	24316352
ICV256	1529814-96-7	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.25µM)	Anti-SARS-CoV	24316352
ICV257	442531-36-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=4.3µM)	Anti-SARS-CoV	24316352
ICV258	1446515-18-9	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=11.83µM)	Anti-SARS-CoV	24316352
ICV259	1529814-97-8	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=67.2µM)	Anti-SARS-CoV	24316352
ICV260	1024151-27-6	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=9.91µM)	Anti-SARS-CoV	24316352
ICV261	897771-25-4	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=13.86µM)	Anti-SARS-CoV	24316352
ICV262	1529815-13-1	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=17.82µM)	Anti-SARS-CoV	24316352
ICV263	1529815-14-2	virus: 3C-like protease	P0DTD1	SARS 3CL(IC50=2.82µM)	Anti-SARS-CoV	24316352
ICV265	865854-05-3	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=1.55µM)	Anti-SARS-CoV-2	32272481
ICV266	61422-45-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=1.82µM)	Anti-SARS-CoV-2	32272481
ICV267	517-89-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=15.75µM)	Anti-SARS-CoV-2	32272481
ICV268	141400-58-0	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=21.39µM)	Anti-SARS-CoV-2	32272481
ICV269	394730-60-0	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=4.13µM)	Anti-SARS-CoV-2	32541865
ICV270	110115-07-6	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=0.97µM)	Anti-SARS-CoV-2	32541865
ICV271	1333312-37-0	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=0.45µM)	Anti-SARS-CoV-2	32541865
ICV272(covalent)	2103278-86-8	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=0.053µM)	Anti-SARS-CoV-2	32321856	6LZE
ICV273(covalent)	2413716-71-7	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(IC50=0.04µM)	Anti-SARS-CoV-2	32321856	6M0K
ICV623(covalent)	2477631-41-5	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.35µM); SARS 3CL(IC50=3.9µM); SARS-CoV-2 3CL(IC50=0.82µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV624(covalent)	2477631-49-3	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.15µM); SARS 3CL(IC50=3.8µM); SARS-CoV-2 3CL(IC50=0.65µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV625(covalent)	2477734-17-9	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.15µM); SARS 3CL(IC50=1.7µM); SARS-CoV-2 3CL(IC50=0.28µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV626(covalent)	2477734-23-7	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.1µM); SARS 3CL(IC50=1.7µM); SARS-CoV-2 3CL(IC50=0.23µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV627(covalent)	2477734-19-1	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.15µM); SARS 3CL(IC50=0.9µM); SARS-CoV-2 3CL(IC50=0.17µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV628(covalent)	2477734-27-1	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.13µM); SARS 3CL(IC50=1µM); SARS-CoV-2 3CL(IC50=0.2µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV629(covalent)	2477631-44-8	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.07µM); SARS 3CL(IC50=2.3µM); SARS-CoV-2 3CL(IC50=0.43µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425	6VH1
ICV630(covalent)	2477631-55-1	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.08µM); SARS 3CL(IC50=2.2µM); SARS-CoV-2 3CL(IC50=0.41µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV631(covalent)	2477631-46-0	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.08µM); SARS 3CL(IC50=1.2µM); SARS-CoV-2 3CL(IC50=0.48µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425
ICV632(covalent)	2477631-59-5	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.1µM); SARS 3CL(IC50=1.1µM); SARS-CoV-2 3CL(IC50=0.45µM)	Anti-SARS-CoV-2/MERS-CoV/SARS-CoV	32747425	"6VH3, 6XMK, 6W2A"
ICV633(covalent)	2477734-16-8	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.33µM)	Anti-MERS-CoV	32747425	6VGY
ICV634(covalent)	2477734-18-0	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.41µM)	Anti-MERS-CoV	32747425	6VGZ
ICV635(covalent)	2477631-42-6	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.75µM)	Anti-MERS-CoV	32747425
ICV636(covalent)	2477631-43-7	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.12µM)	Anti-MERS-CoV	32747425	6VH0
ICV637(covalent)	2477631-45-9	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=2.3µM)	Anti-MERS-CoV	32747425
ICV638(covalent)	2477631-47-1	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.5µM)	Anti-MERS-CoV	32747425
ICV639(covalent)	2477734-21-5	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.32µM)	Anti-MERS-CoV	32747425
ICV640(covalent)	2477734-25-9	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.43µM)	Anti-MERS-CoV	32747425
ICV641(covalent)	2477631-51-7	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.64µM)	Anti-MERS-CoV	32747425
ICV642(covalent)	2477631-53-9	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.16µM)	Anti-MERS-CoV	32747425
ICV643(covalent)	2477631-57-3	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=1.9µM)	Anti-MERS-CoV	32747425	6VH2
ICV644(covalent)	2477631-61-9	virus: 3C-like protease	P0DTD1	MERS 3CL(IC50=0.4µM)	Anti-MERS-CoV	32747425
ICV656	790299-79-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2(EC50=3.2µM) A549 cell	Anti-SARS-CoV-2	32908976	7JU7
ICV662	856242-68-7	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(Ki=0.099µM)	Anti-SARS-CoV-2	19144641	2ZU5
ICV663	856242-51-8	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(Ki=0.038µM)	Anti-SARS-CoV-2	19144641	2ZU4
ICV664	884650-97-9	virus: 3C-like protease	P0DTD1	HCoV-229E 3CL(Ki=1.11µM); SARS-CoV 3CL(Ki=10.7µM)	Anti-HCoV-229E/SARS-CoV	16128623	1WOF
ICV665	884650-98-0	virus: 3C-like protease	P0DTD1	HCoV-229E 3CL(Ki=1.67µM); SARS-CoV 3CL(Ki=9.0µM)	Anti-HCoV-229E/SARS-CoV	16128623/32272481	"2AMQ, 2HOB, 6LU7, 7BQY"
ICV666	1177902-76-9	virus: 3C-like protease	P0DTD1	HCoV-229E 3CL(Ki=0.9µM); SARS-CoV 3CL(Ki=6.7µM)	Anti-HCoV-229E/SARS-CoV	16128623	2AMD
ICV667	884651-00-7	virus: 3C-like protease	P0DTD1	NA	Anti-SARS-CoV	16128623	2D2D
ICV668(covalent)	950886-28-9	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(Kic=250nM)	Anti-SARS-CoV	17599357	"2Z3C, 2Z3D, 2Z3E"
ICV669	219765-20-5	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(IC50=0.3µM)	Anti-SARS-CoV	16913704	2GZ7
ICV670	468726-63-8	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(IC50=3µM)	Anti-SARS-CoV	16913704	2GZ8
ICV671	1033334-15-4	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(IC50=6.2µM)	Anti-SARS-CoV	24080461	4MDS
ICV673(covalent)	870153-29-0	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=0.27nM); HCoV-NL63(Ki=0.77nM); HCoV-229E(Ki=1.5nM); FIPV(Ki=0.12nM); HCoV-HKU1(Ki=0.85nM; HCoV-OC43(Ki=0.51nM)	Anti-SARS-CoV-2/HCoV-NL63/HCoV-229E/FIPV/HCoV-HKU1/HCoV-OC43	32935104	6XHM
ICV674	2468015-78-1	virus: 3C-like protease	P0DTD1	SARS-CoV-2(EC50=3.8µM) Vero E6; HCoV-229E(EC50=0.058µM) MRC-5	Anti-SARS-CoV-2/HCoV-229E	32935104
ICV677	58-32-2	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=0.04µM); SARS-CoV-2 3CL(IC50=0.6µM)	Anti-SARS-CoV-2	33051297
ICV678	145040-37-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=0.18µM); SARS-CoV-2 3CL(IC50=2.8µM)	Anti-SARS-CoV-2	33051297
ICV679	151767-02-1	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=0.48µM); SARS-CoV-2 3CL(IC50=7.3µM)	Anti-SARS-CoV-2	33051297
ICV681	79-57-2	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=0.99µM); SARS-CoV-2 3CL(IC50=15.2µM)	Anti-SARS-CoV-2	33051297
ICV682	175865-60-8	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=1.09µM); SARS-CoV-2 3CL(IC50=16.7µM)	Anti-SARS-CoV-2	33051297
ICV683	78628-28-1	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=1.33µM); SARS-CoV-2 3CL(IC50=20.3µM)	Anti-SARS-CoV-2	33051297
ICV684	73590-58-6	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=1.37µM); SARS-CoV-2 3CL(IC50=21µM)	Anti-SARS-CoV-2	33051297
ICV685	150378-17-9	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=2.82µM); SARS-CoV-2 3CL(IC50=43.1µM)	Anti-SARS-CoV-2	33051297
ICV686	144-80-9	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=3.27µM); SARS-CoV-2 3CL(IC50=50µM)	Anti-SARS-CoV-2	33051297
ICV687	51481-61-9	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=3.27µM); SARS-CoV-2 3CL(IC50=50µM)	Anti-SARS-CoV-2	33051297
ICV688	176161-24-3	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL(Ki=3.27µM); SARS-CoV-2 3CL(IC50=50µM)	Anti-SARS-CoV-2	33051297
ICV704	28831-65-4	virus: 3C-like protease	P0DTD1	SARS-CoV-2 t3CL(IC50=32µM); n3CL(IC50=161µM)	Anti-SARS-CoV-2	33350010
ICV705	20283-92-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 t3CL(IC50=10µM); n3CL(IC50=203µM)	Anti-SARS-CoV-2	33350010
ICV706	96574-01-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 t3CL(IC50=4.8µM); n3CL(IC50=65µM)	Anti-SARS-CoV-2	33350010
ICV707	115841-09-3	virus: 3C-like protease	P0DTD1	SARS-CoV-2 t3CL(IC50=91µM); n3CL(IC50=87µM)	Anti-SARS-CoV-2	33350010
ICV708	121521-90-2	virus: 3C-like protease	P0DTD1	SARS-CoV-2 t3CL(IC50=12µM); n3CL(IC50=109µM)	Anti-SARS-CoV-2	33350010
ICV710	527-95-7	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(IC50=33µM)	Anti-SARS-CoV	31724441
ICV711	28978-02-1	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(IC50=38µM)	Anti-SARS-CoV	31724441
ICV712	17306-46-6	virus: 3C-like protease	P0DTD1	SARS-CoV 3CL(IC50=27µM)	Anti-SARS-CoV	31724441
ICV725	1429218-79-0	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=0.045µM)	Anti-SARS-CoV-2	33393116/32541865
ICV726	1802664-84-1	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=0.042µM)	Anti-SARS-CoV-2	33393116/32541865
ICV727	2589736-94-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=0.012µM)	Anti-SARS-CoV-2	33393116/32541865
ICV729	1401-55-4	human: TMPRSS2	P0DTD1, O15393	"SARS-CoV-2 3CL(Kd=1.1mM, IC50=13.4mM); SARS-CoV-2 TMPRSS2(Kd=1.77mM, IC50=2.31mM)"	Anti-SARS-CoV-2	33415017
ICV733	134308-13-7	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=7.9µM)	Anti-SARS-CoV-2	33526482
ICV739	402957-28-2	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=47.4µM)	Anti-SARS-CoV-2	33538596
ICV740	1216941-48-8	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=44.4µM)	Anti-SARS-CoV-2	33538596
ICV741	630420-16-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=77.4µM)	Anti-SARS-CoV-2	33538596
ICV742	394730-60-0	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=8.9µM)	Anti-SARS-CoV-2	33538596
ICV743	923604-59-5	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=48.2µM)	Anti-SARS-CoV-2	33538596
ICV744	865466-24-6	virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=6.1µM)	Anti-SARS-CoV-2	33538596
ICV746		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=453nM)	Anti-SARS-CoV-2	33602867
ICV747		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=52.1nM)	Anti-SARS-CoV-2	33602867
ICV748		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=16.5nM)	Anti-SARS-CoV-2	33602867
ICV749		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=18.5nM)	Anti-SARS-CoV-2	33602867
ICV750		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=13.2nM)	Anti-SARS-CoV-2	33602867
ICV751		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=14.5nM)	Anti-SARS-CoV-2	33602867
ICV752		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=43.3nM)	Anti-SARS-CoV-2	33602867
ICV753		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=37.2nM)	Anti-SARS-CoV-2	33602867
ICV754		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=15.2nM); SARS-CoV-2 (EC50=35.3nM) Huh7 cell	Anti-SARS-CoV-2	33602867
ICV755		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=50.8nM)	Anti-SARS-CoV-2	33602867
ICV756		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=13.3nM)	Anti-SARS-CoV-2	33602867
ICV757		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=19nM); SARS-CoV-2 (EC50=96.7nM) Huh7 cell	Anti-SARS-CoV-2	33602867
ICV758		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=12.4nM)	Anti-SARS-CoV-2	33602867
ICV759		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=13nM); SARS-CoV-2 (EC50=84.5nM) Huh7 cell	Anti-SARS-CoV-2	33602867
ICV760		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=748.5nM)	Anti-SARS-CoV-2	33602867
ICV761		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=153.1nM)	Anti-SARS-CoV-2	33602867
ICV762		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=298.8nM)	Anti-SARS-CoV-2	33602867
ICV763		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=525.9nM)	Anti-SARS-CoV-2	33602867
ICV764		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=195.6nM)	Anti-SARS-CoV-2	33602867
ICV765		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=375nM)	Anti-SARS-CoV-2	33602867
ICV766		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=7.6nM)	Anti-SARS-CoV-2	33602867
ICV767		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=17.4nM)	Anti-SARS-CoV-2	33602867
ICV768(covalent)		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=7.6nM)	Anti-SARS-CoV-2	33602867
ICV769		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=378.2nM)	Anti-SARS-CoV-2	33602867
ICV770		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=36.2nM)	Anti-SARS-CoV-2	33602867
ICV771		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=69.1nM)	Anti-SARS-CoV-2	33602867
ICV772		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=93.5nM)	Anti-SARS-CoV-2	33602867
ICV773		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=9.2nM); SARS-CoV-2 (EC50=42nM) Huh7 cell	Anti-SARS-CoV-2	33602867
ICV774		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=34.7nM)	Anti-SARS-CoV-2	33602867
ICV775		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=17.2nM); SARS-CoV-2 (EC50=31nM) Huh7 cell	Anti-SARS-CoV-2	33602867
ICV776		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=30nM); SARS-CoV-2 (EC50=62.1nM) Huh7 cell	Anti-SARS-CoV-2	33602867
ICV777		virus: 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=19.7nM)	Anti-SARS-CoV-2	33602867
ICV274	757936-23-5	virus: Papain-like protease	P0DTD1	MERS PL(IC50=20µM)	Anti-MERS-CoV	30940566
ICV275	1440897-95-9	virus: Papain-like protease	P0DTD1	SARS PL(IC50=6.2µM)	Anti-SARS-CoV	23623680
ICV276	1440897-99-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=6.1µM)	Anti-SARS-CoV	23623680
ICV277	1440898-03-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=11.6µM)	Anti-SARS-CoV	23623680
ICV278	1440898-07-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=12.5µM)	Anti-SARS-CoV	23623680
ICV279	174818-72-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=9.5µM)	Anti-SARS-CoV	23623680
ICV280	102818-90-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=9.2µM)	Anti-SARS-CoV	23623680
ICV281	126026-28-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=13.2µM)	Anti-SARS-CoV	23623680
ICV282	1011468-87-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=12.7µM)	Anti-SARS-CoV	23623680
ICV283	97126-57-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=14.4µM)	Anti-SARS-CoV	23623680
ICV284	73676-38-7	virus: Papain-like protease	P0DTD1	SARS PL(IC50=10.4µM)	Anti-SARS-CoV	23623680
ICV285	1005517-27-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=13.9µM)	Anti-SARS-CoV	22971649
ICV286	41137-86-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=7.8µM)	Anti-SARS-CoV	22971649
ICV287	55303-93-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=20.1µM)	Anti-SARS-CoV	22971649
ICV288	211126-61-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=12.3µM)	Anti-SARS-CoV	22971649
ICV289	229623-78-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=8µM)	Anti-SARS-CoV	22971649
ICV290	211126-58-8	virus: Papain-like protease	P0DTD1	SARS PL(IC50=9.1µM)	Anti-SARS-CoV	22971649
ICV291	104061-29-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=6.2µM)	Anti-SARS-CoV	22971649
ICV292	1033618-23-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=59.8µM)	Anti-SARS-CoV	22971649
ICV293	458-37-7	virus: Papain-like protease	P0DTD1	SARS PL(IC50=5.7µM)	Anti-SARS-CoV	22971649
ICV294	695175-00-9	virus: Papain-like protease	P0DTD1	SARS PL(IC50=20.1µM); SARS-CoV-2 PL(IC50=23.5µM)	Anti-SARS-CoV/SARS-CoV-2	18852458/32428392
ICV295	1093070-11-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=14.5µM)	Anti-SARS-CoV	18852458
ICV296	1184301-90-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=14.8µM)	Anti-SARS-CoV	19645480
ICV297	35825-57-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.8µM)	Anti-SARS-CoV	22884354
ICV298	41137-87-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=4.1µM)	Anti-SARS-CoV	22971649
ICV299	1440898-12-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=5µM)	Anti-SARS-CoV	23623680
ICV300	1093070-10-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=8.7µM)	Anti-SARS-CoV	18852458
ICV301	1184301-91-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=29.1µM)	Anti-SARS-CoV	19645480
ICV302	1184301-92-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=90µM)	Anti-SARS-CoV	19645480
ICV303	1184301-93-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=13.5µM)	Anti-SARS-CoV	19645480
ICV304	1184301-95-8	virus: Papain-like protease	P0DTD1	SARS PL(IC50=12.1µM)	Anti-SARS-CoV	19645480
ICV305	1184301-71-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=46.1µM)	Anti-SARS-CoV	19645480
ICV306	1208112-23-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=22.6µM)	Anti-SARS-CoV	19645480
ICV307	1184301-75-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=24.8µM)	Anti-SARS-CoV	19645480
ICV308	1184301-78-7	virus: Papain-like protease	P0DTD1	SARS PL(IC50=11.1µM)	Anti-SARS-CoV	19645480
ICV309	1184301-80-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=5.2µM)	Anti-SARS-CoV	19645480
ICV310	1184301-83-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=2.7µM)	Anti-SARS-CoV	19645480
ICV311	1184301-79-8	virus: Papain-like protease	P0DTD1	SARS PL(IC50=1.4µM)	Anti-SARS-CoV	19645480
ICV312	1184301-87-8	virus: Papain-like protease	P0DTD1	SARS PL(IC50=4.8µM)	Anti-SARS-CoV	19645480
ICV313	429634-26-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=59.2µM)	Anti-SARS-CoV	20527968
ICV314	1233939-62-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=30µM)	Anti-SARS-CoV	20527968
ICV315	1233939-84-8	virus: Papain-like protease	P0DTD1	SARS PL(IC50=1.21µM); SARS(EC50=11.6µM) Vero E6	Anti-SARS-CoV	20527968
ICV316	1233939-85-9	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.34µM); SARS(EC50=9.7µM) Vero E6	Anti-SARS-CoV	20527968
ICV317	1233939-86-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.34µM); SARS(EC50=10.2µM) Vero E6	Anti-SARS-CoV	20527968
ICV318	1233939-87-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=13.2µM)	Anti-SARS-CoV	20527968
ICV319	1233939-88-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=34.8µM)	Anti-SARS-CoV	20527968
ICV320	1233939-89-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=5.8µM)	Anti-SARS-CoV	20527968
ICV321	1234195-91-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.32µM); SARS(EC50=9.1µM) Vero E6	Anti-SARS-CoV	20527968	3MJ5
ICV322	1581755-26-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=17.2µM)	Anti-SARS-CoV	24568342
ICV323	1581755-27-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=32µM)	Anti-SARS-CoV	24568342
ICV324	1581755-30-7	virus: Papain-like protease	P0DTD1	SARS PL(IC50=2.2µM)	Anti-SARS-CoV	24568342
ICV325	1581755-31-8	virus: Papain-like protease	P0DTD1	SARS PL(IC50=13.5µM)	Anti-SARS-CoV	24568342
ICV326	1581755-32-9	virus: Papain-like protease	P0DTD1	SARS PL(IC50=12.7µM)	Anti-SARS-CoV	24568342
ICV327	1581755-34-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=18µM)	Anti-SARS-CoV	24568342
ICV328	1581755-33-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=1.9µM)	Anti-SARS-CoV	24568342
ICV329	1581755-35-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.47µM)	Anti-SARS-CoV	24568342
ICV330	1581755-36-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.6µM)	Anti-SARS-CoV	24568342
ICV331	1581755-37-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.63µM)	Anti-SARS-CoV	24568342
ICV332	1581755-38-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=5.7µM)	Anti-SARS-CoV	24568342
ICV333	1581755-39-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.39µM)	Anti-SARS-CoV	24568342
ICV334	1581755-40-9	virus: Papain-like protease	P0DTD1	SARS PL(IC50=20.4µM)	Anti-SARS-CoV	24568342
ICV335	1581755-41-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=27.2µM)	Anti-SARS-CoV	24568342
ICV336	1581755-42-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.58µM)	Anti-SARS-CoV	24568342
ICV337	1581755-43-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=29.2µM)	Anti-SARS-CoV	24568342
ICV338	1581755-44-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.49µM)	Anti-SARS-CoV	24568342	4OVZ
ICV339	1581755-45-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.15µM)	Anti-SARS-CoV	24568342	4OW0
ICV340	1581755-46-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=7µM)	Anti-SARS-CoV	24568342
ICV341	1581755-47-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=4.5µM)	Anti-SARS-CoV	24568342
ICV342	1581755-48-7	virus: Papain-like protease	P0DTD1	SARS PL(IC50=6.8µM)	Anti-SARS-CoV	24568342
ICV343	1581755-49-8	virus: Papain-like protease	P0DTD1	SARS PL(IC50=30.8µM)	Anti-SARS-CoV	24568342
ICV344	1581755-50-1	virus: Papain-like protease	P0DTD1	SARS PL(IC50=26.3µM)	Anti-SARS-CoV	24568342
ICV345	1581755-51-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=18.3µM)	Anti-SARS-CoV	24568342
ICV346	1581755-52-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.35µM)	Anti-SARS-CoV	24568342
ICV347	1581755-53-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=1.6µM)	Anti-SARS-CoV	24568342
ICV348	1581755-54-5	virus: Papain-like protease	P0DTD1	SARS PL(IC50=1.9µM)	Anti-SARS-CoV	24568342
ICV349	50-44-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50=21.6µM)	Anti-SARS-CoV	18313035
ICV350	154-42-7	virus: Papain-like protease	P0DTD1	SARS PL(IC50=5µM)	Anti-SARS-CoV	18313035
ICV351	128-53-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=4.4µM)	Anti-SARS-CoV	18313035
ICV352	1184301-89-0	virus: Papain-like protease	P0DTD1	SARS PL(IC50=1.3µM); SARS(EC50=5.2µM) Vero E6	Anti-SARS-CoV	19645480
ICV353	1184301-69-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.46µM); SARS(EC50=6.0µM) Vero E6	Anti-SARS-CoV	19645480
ICV354	1233939-90-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.56µM); SARS(EC50=9.1µM) Vero E6	Anti-SARS-CoV	20527968
ICV355	14926-00-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50<50µM)	Anti-SARS-CoV	25746232
ICV356	922098-04-2	virus: Papain-like protease	P0DTD1	SARS PL(IC50<50µM)	Anti-SARS-CoV	25746232
ICV357	1093070-16-6	virus: Papain-like protease	P0DTD1	SARS PL(IC50=0.6µM); SARS (EC50=14.5µM) Vero E6;SARS-CoV-2(IC50=2.4µM)	Anti-SARS-CoV/SARS-CoV-2	18852458/32428392	"7CMD, 7CJM, 3E9S"
ICV358	1093070-14-4	virus: Papain-like protease	P0DTD1	SARS PL(IC50=2.6µM); SARS(EC50=13.1µM) Vero E6; SARS-CoV-2(IC50=5µM)	Anti-SARS-CoV/SARS-CoV-2	18852458/32428392
ICV359	1093070-13-3	virus: Papain-like protease	P0DTD1	SARS PL(IC50=2.3µM); SARS(EC50=10µM) Vero E6	Anti-SARS-CoV	18852458
ICV675(covalent)	NA	virus: Papain-like protease	P0DTD1	NA	Anti-SARS-CoV-2	33067239	6WUU
ICV676(covalent)	NA	virus: Papain-like protease	P0DTD1	NA	Anti-SARS-CoV-2	33067239	6WX4
ICV713	19879-30-2	virus: Papain-like protease	P0DTD1	SARS-CoV PL(IC50=38.4µM)	Anti-SARS-CoV	23323951
ICV714	41060-15-5	virus: Papain-like protease	P0DTD1	SARS-CoV PL(IC50=18.3µM)	Anti-SARS-CoV	23323951
ICV715	20784-50-3	virus: Papain-like protease	P0DTD1	SARS-CoV PL(IC50=7.3µM)	Anti-SARS-CoV	23323951
ICV716	20784-60-5	virus: Papain-like protease	P0DTD1	SARS-CoV PL(IC50=10.1µM)	Anti-SARS-CoV	23323951
ICV717	18642-23-4	virus: Papain-like protease	P0DTD1	SARS-CoV PL(IC50=4.2µM)	Anti-SARS-CoV	23323951
ICV718	775351-88-7	virus: Papain-like protease	P0DTD1	SARS-CoV PL(IC50=32.3µM)	Anti-SARS-CoV	23323951
ICV728	1309129-60-9	virus: Papain-like protease	P0DTD1	SARS-CoV PL (IC50>200µM)	Anti-SARS-CoV-2	33393116
ICV736	10262-69-8	virus: Papain-like protease	P0DTD1	SARS-CoV-2 PL (IC50=9.7µM)	Anti-SARS-CoV-2	33526482
ICV737	20347-71-1	virus: Papain-like protease	P0DTD1	SARS-CoV-2 PL (IC50=2.4µM)	Anti-SARS-CoV-2	33526482
ICV360	568-72-9	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS PL(IC50=1.6µM); SARS 3CL(IC50=89.1µM)	Anti-SARS-CoV	22884354
ICV361	17397-93-2	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS PL(IC50=10.7µM); SARS 3CL(IC50=24.8µM)	Anti-SARS-CoV	22884354
ICV362	18887-19-9	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS PL(IC50=9.2µM); SARS 3CL(IC50=21.1µM)	Anti-SARS-CoV	22884354
ICV363	568-73-0	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS PL(IC50=8.8µM); SARS 3CL(IC50=38.7µM)	Anti-SARS-CoV	22884354
ICV364	87205-99-0	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS PL(IC50=4.9µM); SARS 3CL(IC50=14.4µM)	Anti-SARS-CoV	22884354
ICV365	27210-57-7	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS PL(IC50=30µM); SARS 3CL(IC50=21.1µM)	Anti-SARS-CoV	22884354
ICV366	97-77-8	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS PL(IC50=24.1µM); MERS PL(IC50=14.6µM); SARS 3CL(IC50=9.35µM)	Anti-MERS-CoV/SARS-CoV/SARS-CoV-2	29289665/32272481
ICV367	28448-85-3	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=57.8µM); MERS 3CL(IC50=27.9µM); MERS PL(IC50=112.9µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV368	99217-68-2	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=88.1µM); MERS 3CL(IC50=36.2µM); MERS PL(IC50=42.1µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV369	41743-38-8	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=202.7µM); MERS 3CL(IC50=193.7µM); MERS PL(IC50=171.6µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV370	363134-28-5	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=103.6µM); MERS 3CL(IC50=64.5µM); MERS PL(IC50=112.5µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV371	490028-05-2	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=30.2µM); MERS 3CL(IC50=34.7µM); MERS PL(IC50=48.8µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV372	99624-28-9	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=84.8µM); MERS PL(IC50=88.5µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV373	99624-27-8	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=233.3µM); MERS PL(IC50=94.9µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV374	160262-53-3	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=92.4µM); MERS 3CL(IC50=125.7µM); MERS PL(IC50=49.1µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV375	104494-35-1	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=43.3µM); MERS 3CL(IC50=135µM); MERS PL(IC50=39.5µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV376	104778-05-4	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=64.2µM); MERS 3CL(IC50=109.2µM); MERS PL(IC50=55µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV377	961-29-5	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=61.9µM); MERS 3CL(IC50=33.9µM); MERS PL(IC50=82.2µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV378	520-18-3	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=116.3µM); MERS 3CL(IC50=35.3µM); MERS PL(IC50=206.6µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV379	117-39-5	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS 3CL(IC50=52.7µM); MERS 3CL(IC50=34.8µM)	Anti-MERS-CoV/SARS-CoV	28112000
ICV709	2257-9-2	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS-CoV-2 t3CL(IC50=43µM); SARS-CoV-2 PL(IC50=81µM)	Anti-SARS-CoV-2	33350010
ICV734	51-48-9	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=19.2µM); SARS-CoV-2 PL (IC50=15.3µM)	Anti-SARS-CoV-2	33526482
ICV735	89226-50-6	virus: Papain-like protease; 3C-like protease	P0DTD1	SARS-CoV-2 3CL (IC50=10.4µM); SARS-CoV-2 PL (IC50=14.2µM)	Anti-SARS-CoV-2	33526482
ICV380	675104-49-1	virus: Helicase	P0DTD1	SARS RNA(IC50=5.6µM); SARS(EC50=8.95µM)	Anti-SARS-CoV	22733076
ICV381	1750-12-5	virus: Helicase	P0DTD1	MERS-CoV Helicase activity(IC50=12.4µM)	Anti-MERS-CoV	31955138
ICV382	2427582-37-2	virus: Helicase	P0DTD1	MERS-CoV Helicase activity(IC50=5.7µM)	Anti-MERS-CoV	31955138
ICV383	2427582-38-3	virus: Helicase	P0DTD1	MERS-CoV Helicase activity(IC50=3µM)	Anti-MERS-CoV	31955138
ICV384	2427582-39-4	virus: Helicase	P0DTD1	MERS-CoV Helicase activity(IC50=9µM)	Anti-MERS-CoV	31955138
ICV385	2427582-40-7	virus: Helicase	P0DTD1	MERS-CoV Helicase activity(IC50=6.3µM)	Anti-MERS-CoV	31955138
ICV386	2427582-41-8	virus: Helicase	P0DTD1	MERS-CoV Helicase activity(IC50=4.3µM)	Anti-MERS-CoV	31955138
ICV387	2427582-42-9	virus: Helicase	P0DTD1	MERS-CoV Helicase activity(IC50=2.5µM)	Anti-MERS-CoV	31955138
ICV388	807367-44-8	virus: Helicase	P0DTD1	SARS(EC50=6µM)	Anti-SARS-CoV	15380189
ICV389	665026-57-3	virus: Helicase	P0DTD1	SARS Helicase(IC50=3µM)	Anti-SARS-CoV	15797214
ICV390	858956-95-3	virus: Helicase	P0DTD1	SARS Helicase(IC50=7µM)	Anti-SARS-CoV	15797214
ICV391	858956-96-4	virus: Helicase	P0DTD1	SARS Helicase(IC50=2.7µM)	Anti-SARS-CoV	15797214
ICV392	858956-98-6	virus: Helicase	P0DTD1	SARS Helicase(IC50=5.4µM)	Anti-SARS-CoV	15797214
ICV393	529-44-2	virus: Helicase	P0DTD1	SARS nsP13 ATPase activity(IC50=2.71µM)	Anti-SARS-CoV	22578462
ICV394	529-53-3	virus: Helicase	P0DTD1	SARS nsP13 ATPase activity(IC50=0.86µM)	Anti-SARS-CoV	22578462
ICV620	936727-05-8	virus: Nsp13 Helicase	P0DTD1	SARS-CoV-2 (Nsp13 ATPase) (IC50=0.3mM)	Anti-SARS-CoV-2	33052685
ICV621	481-49-2	virus: Nsp13 Helicase	P0DTD1	SARS-CoV-2 (Nsp13 ATPase) (IC50=0.4mM); SARS-CoV-2(EC50=0.13µM) A549 cell	Anti-SARS-CoV-2	33052685/32908976
ICV395	259793-96-9	virus: RNA-dependent RNA polymerase	P0DTD1	SARS-CoV-2(EC50=61.88µM) Vero E6	Anti-SARS-CoV-2	32020029/29511076/24590073/24084488	7AAP
ICV396	39809-25-1	virus: RNA-dependent RNA polymerase	P0DTD1	SARS-CoV-2(EC50=95.96µM) Vero E6	Anti-SARS-CoV-2	32020029/32392072
ICV397	1809249-37-3	virus: RNA-dependent RNA polymerase	P0DTD1	SARS-CoV-2(EC50=0.77µM) Vero E6	Anti-SARS-CoV-2	32020029/32358203	7BV2
ICV398	25526-93-6	virus: RNA-dependent RNA polymerase	P0DTD1	polymerase extension experiments	Anti-SARS-CoV-2	32511320
ICV399	30516-87-1	virus: RNA-dependent RNA polymerase	P0DTD1	polymerase extension experiments	Anti-SARS-CoV-2	32511320
ICV400	379270-37-8	virus: RNA-dependent RNA polymerase	P0DTD1	polymerase extension experiments	Anti-SARS-CoV-2	32511320
ICV401	36791-04-5	virus: RNA-directed RNA polymerase L	P26676	MERS(EC50=9.99µM) Vero cell; SARS-CoV-2(EC50=109.5) Vero E6	Anti-2019-nCoV/MERS-CoV	32020029/24096239/879760
ICV719	146464-95-1	virus: RNA-dependent RNA polymerase	P0DTD1	SARS-CoV-2 (EC50=0.008µM) Vero	Anti-SARS-CoV-2	33382685
ICV720	83905-01-5	virus: RNA-dependent RNA polymerase	P0DTD1	SARS-CoV-2 (EC50=9.453µM) Vero	Anti-SARS-CoV-2	33382685
ICV724	483-18-1	virus: RNA-dependent RNA polymerase	P0DTD1	SARS-CoV-2 (EC50=0.46µM) Vero E6; SARS-CoV-2 (EC50=0.4nM) Vero E6	Anti-SARS-CoV-2	32251767/33452205
ICV730	116533-18-7	virus: RNA-dependent RNA polymerase	P0DTD1	SARS-CoV-2 (IC50=250µg/ml) NHBE cell	Anti-SARS-CoV-2	33469600
ICV745	2349386-89-4	virus: RNA-dependent RNA polymerase	P0DTD1	Clinical trials(NCT04405570/NCT04405739)	Anti-SARS-CoV-2	33273742
ICV402	1063592-32-4	virus: SARS-CoV Frameshifting Pseudoknot	NA	SARS-CoV-1RF(IC50=0.45µM) HEK 293	Anti-SARS-CoV	27307213
ICV403	117704-65-1	virus: Envelope protein; Spike protein	QHD43418.1, P0DTC2	FIPV(EC50=7.8µM) Black TN406HP	Anti-feline infectious peritonitis virus	17704516/17560666
ICV672	1262552-17-9	virus: RNA G-quadruplex(G4s)	NA	NA	Anti-SARS-CoV-2	32939952
ICV701	1160-14-1	virus: viral RNA	NA	SARS-CoV-2(effective at 10µM) Vero E6	Anti-SARS-CoV-2/HCoV-OC43	33299997
ICV702	2237925-61-8	virus: viral RNA	NA	SARS-CoV-2(effective at 50µM) Vero E6; SARS-CoV-2 viral_RNA(IC50=10µM)	Anti-SARS-CoV-2/HCoV-OC43	33299997
ICV703	2237925-69-6	virus: viral RNA	NA	SARS-CoV-2 viral_RNA(IC50=16µM)	Anti-SARS-CoV-2/HCoV-OC43	33299997
ICV721	1009119-64-5	virus: HCV enzyme NS5A	P26662	SARS-CoV-2 (EC50=0.8µM) Vero; SARS-CoV-2 (EC50=0.6µM) Huh-7; SARS-CoV-2 (EC50=1.1µM) Calu-3	Anti-SARS-CoV-2	10.1101/2020.06.15.153411
ICV722	1190307-88-0	virus: HCV enzyme NS5B	Q9WMX2	SARS-CoV-2 (EC50>10µM) Vero; SARS-CoV-2 (EC50=5.1µM) Huh-7; SARS-CoV-2 (EC50=7.3µM) Calu-3	Anti-SARS-CoV-2	10.1101/2020.06.15.153411
ICV404	220127-57-1	human: ABL1 pathway	NA	MERS(EC50=17.689µM) Vero E6; SARS(EC50=9.823µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV405	302962-49-8	human: ABL1 pathway	NA	MERS(EC50=5.468µM) Vero E6; SARS(EC50=2.1µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV406	23435-23-6	human: ACE2	P59594	ACE2 IC50=57µM	Anti-SARS-CoV	15492138
ICV407	883944-52-3	human: ACE2	P59594	SARS(EC50=3.1µM) 293T cell	Anti-SARS-CoV	23678171
ICV408	100434-29-5	human: ACE2	P59594	SARS(EC50=3µM) 293T	Anti-SARS-CoV	15380189
ICV409	50-65-7	human: ATP synthase	NA	MERS(IC=0.55µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV410	71-63-6	human: "Ca, Na,-exchanging ATPase pump"	NA	MERS(IC=0.16µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV411	20830-75-5	human: "Ca, Na,-exchanging ATPase pump"	NA	MERS(IC=0.17µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV412	132866-11-6	human: Calcium channel	NA	MERS(IC=2.36µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV413	105979-17-7	human: Calcium channel	NA	MERS(IC=4.07µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV414	190274-53-4	human: Calpain	NA	SARS(EC50=2µM) Vero 76	Anti-SARS-CoV	15074711
ICV415	88191-84-8	human: Calpain	NA	SARS(EC50=0.5µM) Vero 76	Anti-SARS-CoV	15074711
ICV416	233277-99-1	human: Cathepsin L	P07711	SARS(IC50=0.68nM) 293T-ACE2; HCoV-229E(IC50=1.48nM) 293T-CD13; MERS(IC50=46.12nM) Vero	Anti-SARS-CoV/Anti-MERS-CoV/Anti-HCoV-229E	25666761
ICV417	433212-75-0	human: Cathepsin L	P07711	SARS(EC50=6.7µM) 293T cell	Anti-SARS-CoV	23678171
ICV418	171500-79-1	human: Cathepsin L	P07711	HIV-luc/MERS-CoV-S(IC50=2.99µM); HIV-luc/SARS-CoV-S(IC50=9.64µM)	Anti-MERS-CoV/SARS-CoV	26953343
ICV421	59865-13-3	human: Cyclophilin A	P62937	SARS(EC50=3.3µM) Vero E6; HCoV-NL63(EC50=2.3µM) CaCo-2; HCoV-229E(EC50=2.3µM) Huh-7	Anti-SARS-CoV/HCoV-NL63/HCoV-229E	22046132
ICV422	69-09-0	human: D(2) dopamine receptor	P14416	MERS(EC50=9.514µM) Vero E6; SARS(EC50=12.971µM);Vero E6	Anti-MERS-CoV/SARS-CoV	24841273/23018094
ICV423	1098-60-8	human: D(2) dopamine receptor	P14416	MERS(EC50=5.758µM) Vero E6; SARS(EC50=6.398µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273/239169
ICV424	2751-68-0	human: Dopamine receptor	NA	MERS(EC50=11.2µM) Huh7 cell	Anti-MERS-CoV	29795047
ICV425	60-99-1	human: Dopamine receptor	NA	MERS(EC50=2.5µM) Huh7 cell	Anti-MERS-CoV	29795047
ICV426	54965-24-1	human: Estrogen receptor	P03372	MERS(EC50=10.117µM) Vero E6; SARS(EC50=92.886µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV427	89778-27-8	human: Estrogen receptor	P03372	MERS(EC50=12.915µM) Vero E6; SARS(EC50=11.969µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV428	697235-38-4	human: Eukaryotic initiation factor 4A-I	P60842	MERS(EC50=3nM) MRC-5 cell; HCoV-229E(EC50=1.3nM) MRC-5 cell	Anti-MERS-CoV/HCoV-229E	29258862
ICV429	10246-75-0	human: Histamine H1 receptor	P35367	MERS-CoV(IC50=14.4µM)	Anti-MERS-CoV	29795047/17222324
ICV430	58-33-3	human: Histamine H1 receptor	P35367	MERS(EC50=11.802µM) Vero E6; SARS(EC50=7.545µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273/12657913
ICV431	68844-77-9	human: Histamine H1 receptor	P35367	MERS(EC50=4.884µM) Vero E6; SARS(EC50=5.591µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273/8001268
ICV432	69-44-3	human: Histamine N-methyltransferase	P50135	MERS-CoV(EC50=2.1µM)	Anti-MERS-CoV	29795047/17222819
ICV433	67915-31-5	human: Lanosterol 14-alpha demethylase(Yeast)	P10613	MERS(EC50=12.203µM) Vero E6; SARS(EC50=15.327µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273/1951574
ICV434	13392-28-4	human: Matrix protein 2	P21430	SARS(EC50=8-16µg/ml) fRhK4	Anti-SARS-CoV	15288617/18669647
ICV435	606143-52-6	human: MEK1/2	NA	NA	Anti-MERS-CoV	25487801
ICV436	871700-17-3	human: MEK1/2	NA	NA	Anti-MERS-CoV	25487801/32577649
ICV437	755037-03-7	human: Multiple kinases	NA	MERS(IC=2.31µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV438	52645-53-1	human: Na channel	NA	MERS(IC=3.6µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV439	630-60-4	human: "Na, K-exchanging ATPase pump"	NA	MERS(IC=0.08µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV440	50-55-5	human: Synaptic Vesicular amine transporter	Q05940	SARS(EC50=3.4µM) Vero E6	Anti-SARS-CoV	15226499/17559790
ICV441	379231-04-6	human: Tyrosine kinase	NA	MERS(EC50=2.9µM) Huh7 cell	Anti-MERS-CoV	29795047
ICV689	1187594-09-7	human: Tyrosine kinase	P23458, O60674, P52333	NA	Anti-SARS-CoV-2	32032529
ICV690	641571-10-0	human: Tyrosine kinase	P00519	SARS-CoV-2(EC50=1.88µM) Vero E6	Anti-SARS-CoV-2	33232578
ICV442	26833-87-4	human: 50S ribosomal protein L2	P20276	MERS(EC50=0.0718µM) Vero E6	Anti-MERS-CoV	24841273/19362093
ICV617	1256565-36-2	human: Dihydroorotate dehydrogenase	Q02127	SARS-CoV-2(EC50=1.96nM) Vero E6	Anti-SARS-CoV-2	32793904
ICV618	541550-19-0	human: PIKfyve kinase	Q9Y2I7	SARS-CoV-2(IC=10nM) Vero E6	Anti-SARS-CoV-2	32764148
ICV645	957054-30-7	human: PI3K	NA	SARS-CoV-2(IC50=2.58µM) Caco2	Anti-SARS-CoV-2	32877642
ICV646	1086062-66-9	human: PI3K; mTORC1/2	NA	SARS-CoV-2(IC50=0.014µM) Caco2	Anti-SARS-CoV-2	32877642
ICV647	284461-73-0	human: RAF	NA	SARS-CoV-2(IC50=4.85µM) Caco2	Anti-SARS-CoV-2	32877642
ICV648	946128-88-7	human: RAF; MEK	NA	SARS-CoV-2(IC50=0.6µM) Caco2	Anti-SARS-CoV-2	32877642
ICV649	193275-84-2	human: RAS	NA	SARS-CoV-2(IC50=4.99µM) Caco2	Anti-SARS-CoV-2	32877642
ICV693	53003-10-4	human: p-glycoprotein 1	P08183	"SARS-CoV-2(EC50=0.097µM,IC50=26µM) Vero E6"	Anti-SARS-CoV-2	33248195/21573958
ICV694	17090-79-8	human: p-glycoprotein 1	P08183	"SARS-CoV-2(EC50=0.097µM,IC50=26µM) Vero E6"	Anti-SARS-CoV-2	33248195
ICV731	1140964-99-3	human: PARP	NA	SARS-CoV-2 (EC50=25.5µM) Vero E6	Anti-SARS-CoV-2	33468703
ICV732	137219-37-5	human: eEF1A	P68104	SARS-CoV-2 (IC50=1.62nM) Pneumocyte-like cell; SARS-CoV-2 (IC50=0.7nM) Vero E6	Anti-SARS-CoV-2	33495306
ICV443	2247366-46-5	Unknown	NA	HCoV-229E(EC50=8.95µM) HEL cell	Anti-HCoV-229E	30286952
ICV444	2247366-56-7	Unknown	NA	HCoV-229E(EC50=9.45µM) HEL cell	Anti-HCoV-229E	30286952
ICV445	2247366-59-0	Unknown	NA	HCoV-229E(EC50=9.45µM) HEL cell	Anti-HCoV-229E	30286952
ICV446	2247366-66-9	Unknown	NA	HCoV-229E(EC50=8.9µM) HEL cell	Anti-HCoV-229E	30286952
ICV447	2247366-69-2	Unknown	NA	HCoV-229E(EC50=11.95µM) HEL cell	Anti-HCoV-229E	30286952
ICV448	1851277-89-8	Unknown	NA	SARS(IC50=0.04nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV449	1851279-69-0	Unknown	NA	SARS(IC50=0.11nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV450	1854081-77-8	Unknown	NA	SARS(IC50=0.24nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV451	1851276-84-0	Unknown	NA	SARS(IC50=2.49nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV452	1851280-00-6	Unknown	NA	SARS(IC50=0.07nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV453	1851279-09-8	Unknown	NA	SARS(IC50=0.08nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV454	1851279-71-4	Unknown	NA	SARS(IC50=0.25nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV455	1851276-99-7	Unknown	NA	SARS(IC50=0.16nM) 293T-ACE2 cell	Anti-SARS-CoV	25666761
ICV456	7083-71-8	Unknown	NA	MERS(EC50=0.014µM) Vero E6; SARS(EC50=0.051µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV457	50-63-5	Unknown	NA	MERS(EC50=6.275µM) Vero E6; SARS(EC50=6.538µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV458	747-36-4	Unknown	NA	MERS(EC50=8.279µM) Vero E6; SARS(EC50=7.966µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV459	6398-98-7	Unknown	NA	MERS(EC50=6.212µM) Vero E6; SARS(EC50=1.274µM);Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV460	122111-03-9	Unknown	NA	MERS(EC50=1.216µM) Vero E6; SARS(EC50=4.957µM);Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV461	78-41-1	Unknown	NA	MERS(EC50=5.283µM) Vero E6 cell	Anti-MERS-CoV	24841273
ICV462	22862-76-6	Unknown	NA	MERS(EC50=0.003µM) Vero E6; SARS(EC50=0.191µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV463	132-17-2	Unknown	NA	MERS(EC50=16.627µM) Vero E6; SARS(EC50=21.611µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV464	1179-69-7	Unknown	NA	MERS(EC50=7.865µM) Vero E6	Anti-MERS-CoV	24841273
ICV465	2330832-55-6	Unknown	NA	HCoV-229E(EC50=31µM) HEL 299 cell	Anti-HCoV-229E	31073993
ICV466	2330832-58-9	Unknown	NA	HCoV-229E(EC50=12µM) HEL 299 cell	Anti-HCoV-229E	31073993
ICV467	2330832-84-1	Unknown	NA	HCoV-229E(EC50=28µM) HEL 299 cell	Anti-HCoV-229E	31073993
ICV468	2330832-86-3	Unknown	NA	HCoV-229E(EC50=18µM) HEL 299 cell	Anti-HCoV-229E	31073993
ICV469	2330832-89-6	Unknown	NA	HCoV-229E(EC50=8.1µM) HEL 299 cell	Anti-HCoV-229E	31073993
ICV470	2330832-92-1	Unknown	NA	HCoV-229E(EC50=5.5µM) HEL 299 cell	Anti-HCoV-229E	31073993
ICV471	2330832-97-6	Unknown	NA	HCoV-229E(EC50=6.1µM); HEL 299 cell	Anti-HCoV-229E	31073993
ICV472	548472-68-0	Unknown	NA	MERS-CoV(EC50=6.9µM)	Anti-MERS-CoV	29795047
ICV473	196618-13-0	Unknown	NA	NA	Anti-SARS-CoV-2	32127666
ICV474	1841-19-6	Unknown	NA	MERS(EC50=7.477µM) Vero E6; SARS(EC50=5.963µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV475	5591-45-7	Unknown	NA	MERS(EC50=9.297µM) Vero E6; SARS(EC50=5.316µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV476	146-56-5	Unknown	NA	MERS(EC50=5.868µM) Vero E6; SARS(EC50=21.431µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV477	562-09-4	Unknown	NA	MERS(EC50=12.646µM) Vero E6; SARS(EC50=20.031µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV478	17321-77-6	Unknown	NA	MERS(EC50=9.332µM) Vero E6; SARS(EC50=13.238µM) Vero E6; SARS-CoV-2(EC50=2µM) A549 cell	Anti-MERS-CoV/SARS-CoV/SARS-CoV-2	24841273/32908976
ICV479	425637-18-9	Unknown	NA	MERS(EC50=9.7µM) Huh7 cell	Anti-MERS-CoV	29795047
ICV480	2236598-84-6	Unknown	NA	MERS(EC50=0.2µM) Vero; SARS(EC50=0.5µM) Vero E6	Anti-MERS-CoV/SARS-CoV	31244113
ICV481	1798810-56-6	Unknown	NA	HCoV-NL63(E50=8.8µM) Vero118; MERS-CoV(EC50=27µM) Huh7; MERS-CoV(EC50=23µM) Vero	Anti-HCoV-NL63/MERS-CoV	26048809
ICV482	897-15-4	Unknown	NA	MERS(EC50=3.4µM) Huh7 cell	Anti-MERS-CoV	29795047
ICV483	81525-10-2	Unknown	NA	MERS-S-mediated membrane fusion (IC50=0.1µM); MERS(IC50=0.1nM) Calu3 cell	Anti-MERS-CoV	27550352
ICV484	55981-09-4	Unknown	NA	SARS-CoV-2(EC50=2.12µM) Vero E6	Anti-SARS-CoV-2	32020029
ICV485	52869-18-8	Unknown	NA	SARS(EC50=9.7µM) 293T; SARS(EC50=0.15µM) Vero	Anti-SARS-CoV	23678171
ICV486	501-36-0	Unknown	NA	NA	Anti-MERS-CoV	28193191
ICV487	53230-10-7	Unknown	NA	MERS(EC50=7.416µM) Vero E6; SARS(EC50=15.553µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV488	53179-11-6	Unknown	NA	SARS(EC50=5.9µM) Vero E6; MERS(EC50=4.8µM) Huh 7; HCoV-229E(EC50=4µM)	Anti-MERS-CoV/SARS-CoV/HCoV-229E	24841269
ICV489	131707-23-8	Unknown	NA	SARS-CoV-2(EC50=4.11µM) Vero E6	Anti-2019-nCoV	32373347
ICV490	1954-5-7	Unknown	NA	SARS-CoV-2(EC50=1.13µM) Vero E6	Anti-M/SARS-CoV/2019-nCoV	32020029
ICV491	254435-95-5	Unknown	NA	SARS-CoV(EC50=1.3µM) Vero E6; MERS(EC50=3.6µM) Vero; MERS(EC50=3.4µM) Huh7	Anti-MERS-CoV/SARS-CoV	27840112
ICV492	24280-93-1	Unknown	NA	MERS(EC50=0.17µM) Vero cell	Anti-MERS-CoV	24096239
ICV493	50924-49-7	Unknown	NA	SARS(IC50=3.5µM) Vero E6	Anti-SARS-CoV	15911031
ICV494	159989-64-7	Unknown	NA	SARS(EC50=0.048µM) Vero	Anti-SARS-CoV	15144898
ICV495	608531-54-0	Unknown	NA	SARS(EC50=0.027mg/L) Vero	Anti-SARS-CoV	16242214
ICV496	791074-64-1	Unknown	NA	SARS(EC50=8.9µM) Vero FFM1;SARS(EC50=5.3µM) Vero 6109; SARS(EC50=8.8µM) Caco2 FFM1	Anti-SARS-CoV	26878082/16451084
ICV497	791074-63-0	Unknown	NA	SARS Vero(EC50=3.6µM) FFM1;SARS(EC50=2.5µM) Vero 6109; SARS(EC50=2.4µM) Caco2 FFM1	Anti-SARS-CoV	26878082/16451084
ICV498	877221-67-5	Unknown	NA	SARS(EC50=6.2µM) Vero FFM1;SARS(EC50=6.6µM) Vero 6109; SARS Caco2(EC50=12.6µM) FFM1	Anti-SARS-CoV	26878082/16451084
ICV499	491-70-3	Unknown	NA	SARS(EC50=10.6µM) Vero E6	Anti-SARS-CoV	26878082/15452254
ICV500	79886-50-3	Unknown	NA	SARS(EC50=4.5µM) Vero E6	Anti-SARS-CoV	26878082/15452254
ICV501	161168-74-7	Unknown	NA	SARS(IC50=48.7µM) Vero E6	Anti-SARS-CoV	26878082/17336519
ICV502	126544-47-6	Unknown	NA	SARS-CoV-2(EC50=4.4µM) VeroE6/TMPRSS2 cell	Anti-SARS-CoV-2	10.1101/2020.03.11.987016
ICV503	2001-95-8	Unknown	NA	SARS(EC50=0.85µM) Vero E6	Anti-SARS-CoV	15226499
ICV504	3258-2-4	Unknown	NA	SARS(EC50=10µM) Vero 76	Anti-SARS-CoV	15074711
ICV505	4431-00-9	Unknown	NA	SARS(EC50=0.2mg/ml) Vero	Anti-SARS-CoV	15249217
ICV506	518-82-1	Unknown	NA	SARS Vero E6 at 50µM is 94.12%	Anti-SARS-CoV	19275708
ICV507	1405-86-3	Unknown	NA	SARS(EC50=300mg/ml) Vero	Anti-SARS-CoV	12814717
ICV508	21967-41-9	Unknown	NA	SARS(EC50=12.5-25µg/ml) fRhK4	Anti-SARS-CoV	15288617
ICV509	6805-41-0	Unknown	NA	SARS(EC50=6µM) Vero E6	Anti-SARS-CoV	15226499
ICV510	878479-22-2	Unknown	NA	SARS(EC50=21µM)	Anti-SARS-CoV	16451078
ICV511	878479-24-4	Unknown	NA	SARS(EC50=47µM)	Anti-SARS-CoV	16451078
ICV512	668993-09-7	Unknown	NA	SARS(EC50=57µM) Vero	Anti-SARS-CoV	16675038
ICV513	300582-65-4	Unknown	NA	SARS(EC50=22µM) Vero; FIPV(EC50=20µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV514	158213-44-6	Unknown	NA	SARS(EC50=27µM) Vero	Anti-SARS-CoV	16675038
ICV515	193685-70-0	Unknown	NA	SARS(EC50=54µM) Vero; FIPV(EC50=44µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV519	913553-48-7	Unknown	NA	SARS(EC50=14µM) Vero	Anti-SARS-CoV	16675038
ICV522	913553-50-1	Unknown	NA	SARS(EC50=44µM) Vero	Anti-SARS-CoV	16675038
ICV523	913553-52-3	Unknown	NA	FIPV(EC50=6.9µM) CRFK	Anti-FIPV	16675038
ICV524	913553-56-7	Unknown	NA	SARS(EC50=22µM) Vero	Anti-SARS-CoV	16675038
ICV525	913553-57-8	Unknown	NA	FIPV(EC50=14µM) CRFK	Anti-FIPV	16675038
ICV526	410077-91-7	Unknown	NA	SARS(EC50=30µM) Vero	Anti-SARS-CoV	16675038
ICV527	562105-14-0	Unknown	NA	SARS(EC50=31µM) Vero	Anti-SARS-CoV	16675038
ICV528	410077-94-0	Unknown	NA	SARS(EC50=22µM) Vero; FIPV(EC50=12µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV529	668993-44-0	Unknown	NA	SARS(EC50=50µM) Vero	Anti-SARS-CoV	16675038
ICV530	668993-45-1	Unknown	NA	SARS(EC50=60µM) Vero	Anti-SARS-CoV	16675038
ICV534	562105-20-8	Unknown	NA	SARS(EC50=43µM) Vero; FIPV(EC50=7.5µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV536	855674-07-6	Unknown	NA	SARS(EC50=57µM) Vero	Anti-SARS-CoV	16675038
ICV537	855674-10-1	Unknown	NA	SARS(EC50=51µM) Vero; FIPV(EC50=24µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV538	855674-13-4	Unknown	NA	SARS(EC50=26µM) Vero	Anti-SARS-CoV	16675038
ICV539	913553-65-8	Unknown	NA	SARS(EC50=26µM) Vero	Anti-SARS-CoV	16675038
ICV540	562105-21-9	Unknown	NA	SARS(EC50=35µM) Vero; FIPV(EC50=29µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV541	562105-22-0	Unknown	NA	SARS(EC50=34µM) Vero; FIPV(EC50=14µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV542	562105-23-1	Unknown	NA	SARS(EC50=52µM) Vero; FIPV(EC50=3.6µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV543	562105-24-2	Unknown	NA	SARS(EC50=15µM) Vero	Anti-SARS-CoV	16675038
ICV544	668993-57-5	Unknown	NA	SARS(EC50=32µM) Vero; FIPV(EC50=23µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV545	855674-18-9	Unknown	NA	SARS(EC50=59µM) Vero; FIPV(EC50=48µM) CRFK	Anti-SARS-CoV/FIPV	16675038
ICV546	855674-21-4	Unknown	NA	SARS(EC50=29µM) Vero	Anti-SARS-CoV	16675038
ICV547	79032-48-7	Unknown	NA	SARS(IC50=3.2µM) Vero	Anti-SARS-CoV	18584889
ICV548	285558-52-3	Unknown	NA	SARS(IC50=6.8µM) Vero	Anti-SARS-CoV	18584889
ICV549	442151-31-7	Unknown	NA	SARS(IC50=7.6µM) Vero	Anti-SARS-CoV	18584889
ICV550	202191-43-3	Unknown	NA	SARS(IC50=4.5µM) Vero	Anti-SARS-CoV	18584889
ICV551	1086304-29-1	Unknown	NA	SARS(IC50=11.3µM) Vero	Anti-SARS-CoV	18584889
ICV552	60263-97-0	Unknown	NA	FIPV(EC50=6.6mg/L) Vero E6; SARA(EC50=42mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV553	60264-21-3	Unknown	NA	FIPV(EC50=13mg/L) Vero E6	Anti-FIPV	16387746
ICV554	62381-78-6	Unknown	NA	FIPV(EC50=1.8mg/L) Vero E6; SARA(EC50=65mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV555	84504-46-1	Unknown	NA	FIPV(EC50=3.9mg/L) Vero E6; SARA(EC50=30mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV556	60263-80-1	Unknown	NA	FIPV(EC50=5.8mg/L) Vero E6; SARS(EC50=55mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV557	14694-58-7	Unknown	NA	FIPV(EC50=16mg/L) Vero E6; SARA(EC50=32mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV558	60264-17-7	Unknown	NA	FIPV(EC50=11mg/L) Vero E6	Anti-FIPV	16387746
ICV559	60264-51-9	Unknown	NA	FIPV(EC50=2.4mg/L) Vero E6	Anti-FIPV	16387746
ICV560	60264-18-8	Unknown	NA	SARS(EC50=46µM) Vero E6	Anti-SARS-CoV	16387746
ICV561	84504-49-4	Unknown	NA	FIPV(EC50=3.7mg/L) Vero E6; SARS(EC50=38mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV562	84279-92-5	Unknown	NA	FIPV(EC50=4.3mg/L) Vero E6; SARS(EC50=55mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV563	62382-00-7	Unknown	NA	FIPV(EC50=1.3mg/L) Vero E6	Anti-FIPV	16387746
ICV564	82959-43-1	Unknown	NA	FIPV(EC50=2.2mg/L) Vero E6; SARS(EC50=49mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV565	478619-57-7	Unknown	NA	FIPV(EC50=2.5mg/L) Vero E6	Anti-FIPV	16387746
ICV566	62381-76-4	Unknown	NA	FIPV(EC50=12mg/L) Vero E6; SARS(EC50=51mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV567	62381-89-9	Unknown	NA	SARS(EC50=4.2µM) Vero E6	Anti-SARS-CoV	16387746
ICV568	60264-49-5	Unknown	NA	FIPV(EC50=2.5mg/L) Vero E6	Anti-FIPV	16387746
ICV569	60264-50-8	Unknown	NA	FIPV(EC50=9.8mg/L) Vero E6	Anti-FIPV	16387746
ICV570	60264-47-3	Unknown	NA	FIPV(EC50=3.8mg/L) Vero E6	Anti-FIPV	16387746
ICV571	65333-35-9	Unknown	NA	FIPV(EC50=3.7mg/L) Vero E6	Anti-FIPV	16387746
ICV572	65333-34-8	Unknown	NA	FIPV(EC50=35mg/L) Vero E6	Anti-FIPV	16387746
ICV573	60264-24-6	Unknown	NA	FIPV(EC50=1.2mg/L) Vero E6; SARS(EC50=68mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV574	62382-20-1	Unknown	NA	FIPV(EC50=8mg/L) Vero E6	Anti-FIPV	16387746
ICV575	62382-19-8	Unknown	NA	FIPV(EC50=6.3mg/L) Vero E6	Anti-FIPV	16387746
ICV576	62381-81-1	Unknown	NA	FIPV(EC50=5.3mg/L) Vero E6	Anti-FIPV	16387746
ICV577	62381-94-6	Unknown	NA	FIPV(EC50=16mg/L) Vero E6	Anti-FIPV	16387746
ICV578	60264-12-2	Unknown	NA	FIPV(EC50=5.5mg/L) Vero E6	Anti-FIPV	16387746
ICV579	62381-74-2	Unknown	NA	FIPV(EC50=6.2mg/L) Vero E6; SARS(EC50=35mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV580	60264-11-1	Unknown	NA	FIPV(EC50=3.2mg/L) Vero E6; SARS(EC50=11mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV581	60264-02-0	Unknown	NA	FIPV(EC50=5.9mg/L) Vero E6; SARS(EC50=46mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV582	60264-27-9	Unknown	NA	FIPV(EC50=3.3mg/L) Vero E6	Anti-FIPV	16387746
ICV583	60264-04-2	Unknown	NA	FIPV(EC50=0.87mg/L) Vero E6; SARS(EC50=12mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV584	60264-26-8	Unknown	NA	FIPV(EC50=0.79mg/L) Vero E6; SARS(EC50=17mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV585	62382-08-5	Unknown	NA	FIPV(EC50=2.3mg/L) Vero E6; SARS(EC50=56mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV586	60264-25-7	Unknown	NA	FIPV(EC50=2.9mg/L) Vero E6; SARS(EC50=38mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV587	478619-78-2	Unknown	NA	FIPV(EC50=2.8mg/L) Vero E6; SARS(EC50=16mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV588	60264-43-9	Unknown	NA	FIPV(EC50=41mg/L) Vero E6	Anti-FIPV	16387746
ICV589	62381-80-0	Unknown	NA	FIPV(EC50=3.7mg/L) Vero E6; SARS(EC50=59mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV590	65333-24-6	Unknown	NA	FIPV(EC50=0.29mg/L) Vero E6; SARS(EC50=17mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV591	60264-40-6	Unknown	NA	FIPV(EC50=0.91mg/L) Vero E6; SARS(EC50=20mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV592	62381-75-3	Unknown	NA	FIPV(EC50=10.7mg/L) Vero E6; SARS(EC50=43mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV593	478619-86-2	Unknown	NA	FIPV(EC50=3.3mg/L) Vero E6	Anti-FIPV	16387746
ICV594	478619-94-2	Unknown	NA	FIPV(EC50=3.3mg/L) Vero E6	Anti-FIPV	16387746
ICV595	478619-90-8	Unknown	NA	FIPV(EC50=4.2mg/L) Vero E6; SARS(EC50=11mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV596	60264-13-3	Unknown	NA	FIPV(EC50=1.7mg/L) Vero E6; SARS(EC50=22mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV597	478619-82-8	Unknown	NA	FIPV(EC50=5.0mg/L) Vero E6	Anti-FIPV	16387746
ICV598	62381-79-7	Unknown	NA	FIPV(EC50=3.3mg/L) Vero E6	Anti-FIPV	16387746
ICV599	62381-98-0	Unknown	NA	FIPV(EC50=1.5mg/L) Vero E6	Anti-FIPV	16387746
ICV600	84504-48-3	Unknown	NA	FIPV(EC50=8.1mg/L) Vero E6	Anti-FIPV	16387746
ICV601	65333-40-6	Unknown	NA	SARS(EC50=5.9µM) Vero E6	Anti-SARS-CoV	16387746
ICV602	478620-30-3	Unknown	NA	SARS(EC50=13µM) Vero E6	Anti-SARS-CoV	16387746
ICV603	62381-93-5	Unknown	NA	FIPV(EC50=3.4mg/L) Vero E6; SARS(EC50=36mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV604	478619-98-6	Unknown	NA	FIPV(EC50=12mg/L) Vero E6; SARS(EC50=49mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV605	478620-26-7	Unknown	NA	FIPV(EC50=11mg/L) Vero E6; SARS(EC50=47mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV606	478620-24-5	Unknown	NA	FIPV(EC50=2.8mg/L) Vero E6; SARS(EC50=69mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV607	84950-51-6	Unknown	NA	FIPV(EC50=14mg/L) Vero E6; SARS(EC50=69mg/L) Vero E6	Anti-SARS-CoV/FIPV	16387746
ICV608	95233-18-4	Unknown	NA	MERS(IC50=0.72µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV609	6197-30-4	Unknown	NA	MERS(IC50=3.62µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV610	2277-92-1	Unknown	NA	MERS(IC50=0.07µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV611	66-81-9	Unknown	NA	MERS(EC50=0.189µM) Vero E6; SARS(EC50=0.043µM) Vero E6	Anti-MERS-CoV/SARS-CoV	24841273
ICV612	17575-22-3	Unknown	NA	MERS(IC50=0.19µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV613	52665-69-7	Unknown	NA	"MERS(IC50=0.2µM) Vero; SARS-CoV-2(EC50=0.26µM,IC50=4.7µM) Vero E6"	Anti-MERS-CoV/SARS-CoV-2	10.1101/2020.02.25.965582/33248195
ICV614	143-62-4	Unknown	NA	MERS(IC50=0.29µM) Vero	Anti-MERS-CoV	10.1101/2020.02.25.965582
ICV615	791074-65-2	Unknown	NA	SARS(EC50=6.2µM) Vero	Anti-SARS-CoV	16451084
ICV616	175470-82-3	Unknown	NA	SARS(IC50=14.5µM) Vero	Anti-SARS-CoV	17336519
ICV619	2140-46-7	Unknown	NA	SARS-CoV-2(EC50=3.675µM) Vero	Anti-SARS-CoV-2	32811977
ICV622	110683-10-8	Unknown	NA	SARS-CoV-2(EC50=0.59µM) Caco2	Anti-SARS-CoV-2/MERS-CoV	32923629
ICV650	2709-56-0	Unknown	NA	SARS-CoV-2(EC50=0.56µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV651	739-71-9	Unknown	NA	SARS-CoV-2(EC50=1.5µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV652	231277-92-2	Unknown	NA	SARS-CoV-2(EC50=1.6µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV653	86-13-5	Unknown	NA	SARS-CoV-2(EC50=1.8µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV654	859212-16-1	Unknown	NA	SARS-CoV-2(EC50=2.2µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV655	58581-89-8	Unknown	NA	SARS-CoV-2(EC50=2.4µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV657	242478-37-1	Unknown	NA	SARS-CoV-2(EC50=3.6µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV658	77-23-6	Unknown	NA	SARS-CoV-2(EC50=3.6µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV659	54063-53-5	Unknown	NA	SARS-CoV-2(EC50=3.7µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV660	84449-90-1	Unknown	NA	SARS-CoV-2(EC50=3.8µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV661	163521-12-8	Unknown	NA	SARS-CoV-2(EC50=4.5µM) A549 cell	Anti-SARS-CoV-2	32908976
ICV691	36505-48-3	Unknown	NA	SARS-CoV-2(EC50=0.014µM,IC50=8.2µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV692	25999-31-9	Unknown	NA	SARS-CoV-2(EC50=0.36µM,IC50=24µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV695	65101-87-3	Unknown	NA	SARS-CoV-2(EC50=0.066µM,IC50=7.2µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV696	56092-81-0	Unknown	NA	SARS-CoV-2(EC50=3µM,IC50=15µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV697	66513-28-8	Unknown	NA	SARS-CoV-2(EC50=0.63µM,IC50=30µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV698	28380-24-7	Unknown	NA	SARS-CoV-2(EC50=0.089µM,IC50=7.4µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV699	79356-08-4	Unknown	NA	SARS-CoV-2(EC50=0.064µM,IC50=20µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV700	55134-13-9	Unknown	NA	SARS-CoV-2(EC50=0.071µM,IC50=7.4µM) Vero E6	Anti-SARS-CoV-2	33248195
ICV723	863329-66-2	Unknown	NA	SARS-CoV-2 (EC50>10µM) Vero; SARS-CoV-2 (EC50>10µM) Huh-7; SARS-CoV-2 (EC50=9.3µM) Calu-3	Anti-SARS-CoV-2	10.1101/2020.06.15.153411
ICV738	1998705-64-8	Unknown	NA	HCoV-229E(EC50=1.8µM) BHK-21; SARS-CoV-2(EC90=0.47µM) HAE	Anti-SARS-CoV-2/HCoV-229E/HCoV-OC43/MERS-CoV/SARS-CoV	33558299
ICV778	113507-06-5	Unknown	NA	SARS-CoV-2(IC50=3.1µM) Vero E6	Anti-SARS-CoV-2	33452205
ICV779	873054-44-5	Unknown	NA	SARS-CoV-2(IC50=3.7µM) Vero E6	Anti-SARS-CoV-2	33452205
ICV780	123524-52-7	Unknown	NA	SARS-CoV-2(IC50=5.3µM) Vero E6	Anti-SARS-CoV-2	33452205
ICV781	26864-56-2	Unknown	NA	SARS-CoV-2(IC50=2.4µM) Vero E6	Anti-SARS-CoV-2	33452205
ICV782	141626-36-0	Unknown	NA	SARS-CoV-2(IC50=4.5µM) Vero E6	Anti-SARS-CoV-2	33452205

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