D3DistalMutation

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D3DistalMutation ( >10Å )

DistalMutation ( >10Å )

Mutation ( <10Å )

decrease activity

Enzyme Name	Abbreviation	Uniprot ID	PDB ID	PDB Chain	Mutation Resi	Mutation Type	Active Site Resi	Active Resn	dist (Å)	Activity Change	References
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	A	362	Y->F	313	D	10.12	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	B	362	Y->F	313	D	10.37	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	C	362	Y->F	313	D	10.07	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	D	362	Y->F	313	D	10.32	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zut	A	362	Y->F	313	D	10.29	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zut	B	362	Y->F	313	D	10.99	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zut	C	362	Y->F	313	D	10.95	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zut	D	362	Y->F	313	D	10.53	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuu	A	362	Y->F	313	D	10.01	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuu	B	362	Y->F	313	D	10.87	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuu	C	362	Y->F	313	D	10.67	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuu	D	362	Y->F	313	D	10.33	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuv	B	362	Y->F	313	D	10.3	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuw	A	362	Y->F	313	D	10.09	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuw	B	362	Y->F	313	D	10.57	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zuw	C	362	Y->F	313	D	10.69	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	3wfz	A	362	Y->F	313	D	10.19	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	3wfz	B	362	Y->F	313	D	10.24	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	3wfz	D	362	Y->F	313	D	10.29	Strong decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	A	364	F->N	313	D	13.85	Decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	B	364	F->N	313	D	14.24	Decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	C	364	F->N	313	D	13.84	Decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zus	D	364	F->N	313	D	14.32	Decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zut	A	364	F->N	313	D	13.42	Decrease in activity.	19124470
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase	lnpA	E8MF13	2zut	B	364	F->N	313	D	13.67	Decrease in activity.	19124470

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D3DistalMutation ( >10Å )

DistalMutation ( >10Å )

Mutation ( <10Å )

decrease activity