Introduction

介绍

D3EGFRdb is a clinical database about the characteristics and outcomes of EGFR-mutated lung cancer patients treated with EGFR-TKIs. At present, all of the clinical cases are from literature reports, which are annotated with a definite response of complete response (CR), partial response (PR), stable disease (SD), and progressive disease (PD) and other clinicopathologic characteristics. Users can query a certain mutation type to obtain the effects of existing drug therapy, as an important reference for drug recommendation.

D3EGFRdb是一个有关EGFR突变肺癌患者的临床特征和治疗结果的临床案例数据库,收录的患者均接受EGFR酪氨酸激酶抑制剂作为治疗方案。目前,所有的临床病例均来自文献报道,并注明了完全缓解(CR)、部分缓解(PR)、疾病稳定(SD)和疾病进展(PD)的明确反应以及其他临床病理特征。用户可以查询某种突变类型以获得现有药物的治疗情况,作为选择药物的重要参考。

 

Examples:
Point mutation: L858R
Deletion mutation: E746_A750del,V834del
Insert mutation: D770insSVD
Duplicate mutation: A767dupASV
Deletion-insertion mutation: L747_P753delinsS, D770delinsGY
Complex mutation: E746_A750del+L858R

输入格式举例:
点突变:L858R
缺失突变:E746_A750del, V834del
插入突变:D770insSVD
重复突变:A767dupASV
插入缺失突变:L747_P753delinsS, D770delinsGY
复杂突变:E746_A750del+L858R