| 1 |
ICV439 |
39.16 | 71.65% | 54.65% |
human: "Na, K-exchanging ATPase pump" | NA | MERS(IC=0.08µM) Vero |
| 2 |
ICV410 |
32.5 | 60.86% | 53.41% |
human: "Ca, Na,-exchanging ATPase pump" | NA | MERS(IC=0.16µM) Vero |
| 3 |
ICV411 |
31.31 | 58.63% | 53.41% |
human: "Ca, Na,-exchanging ATPase pump" | NA | MERS(IC=0.17µM) Vero |
| 4 |
ICV150 |
26.65 | 76.72% | 34.74% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=5.5µM) |
| 5 |
ICV153 |
26.23 | 77.43% | 33.87% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=10µM) |
| 6 |
ICV290 |
23.35 | 65.93% | 35.42% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=9.1µM) |
| 7 |
ICV152 |
23.21 | 79.44% | 29.21% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=2.6µM) |
| 8 |
ICV149 |
22.56 | 75.75% | 29.79% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=10.3µM) |
| 9 |
ICV391 |
22.08 | 66.92% | 33% |
virus: Helicase | P0DTD1 | SARS Helicase(IC50=2.7µM) |
| 10 |
ICV289 |
21.86 | 61.72% | 35.42% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=8µM) |
| 11 |
ICV151 |
21.44 | 79.75% | 26.88% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=9.9µM) |
| 12 |
ICV287 |
19.47 | 61.83% | 31.48% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=20.1µM) |
| 13 |
ICV438 |
14.92 | 66.84% | 22.32% |
human: Na channel | NA | MERS(IC=3.6µM) Vero |
| 14 |
ICV154 |
14.43 | 63.32% | 22.79% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=25µM) |
| 15 |
ICV73 |
14.19 | 68.19% | 20.81% |
virus: 3C-like protease | P0DTD1 | Replicon (BHK) (IC50=2µM); SARS(IC50=8.9µM) Vero |
| 16 |
ICV389 |
14.05 | 65.56% | 21.43% |
virus: Helicase | P0DTD1 | SARS Helicase(IC50=3µM) |
| 17 |
ICV364 |
13.8 | 74.73% | 18.47% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=4.9µM); SARS 3CL(IC50=14.4µM) |
| 18 |
ICV292 |
13.62 | 66.16% | 20.59% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=59.8µM) |
| 19 |
ICV72 |
13.47 | 65.56% | 20.54% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=2.5µM) |
| 20 |
ICV298 |
13.02 | 70.87% | 18.37% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=4.1µM) |
