| 1 |
ICV300 |
26.33 | 78.01% | 33.75% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=8.7µM) |
| 2 |
ICV305 |
26.32 | 75.19% | 35% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=46.1µM) |
| 3 |
ICV294 |
26.31 | 77.97% | 33.75% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=20.1µM); SARS-CoV-2 PL(IC50=23.5µM) |
| 4 |
ICV304 |
26.23 | 75.89% | 34.57% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=12.1µM) |
| 5 |
ICV175 |
26.2 | 85.14% | 30.77% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=0.03µM) |
| 6 |
ICV301 |
25.91 | 71.26% | 36.36% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=29.1µM) |
| 7 |
ICV353 |
25.72 | 77.17% | 33.33% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=0.46µM); SARS(EC50=6.0µM) Vero E6 |
| 8 |
ICV172 |
25.41 | 80.14% | 31.71% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=19.5µM) |
| 9 |
ICV296 |
25.06 | 70.71% | 35.44% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=14.8µM) |
| 10 |
ICV174 |
24.66 | 80.47% | 30.65% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=12.1µM) |
| 11 |
ICV310 |
24.62 | 70.34% | 35% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=2.7µM) |
| 12 |
ICV173 |
24.61 | 81.61% | 30.16% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=7.5µM) |
| 13 |
ICV168 |
24.56 | 80.13% | 30.65% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=17.4µM) |
| 14 |
ICV169 |
23.91 | 77.87% | 30.71% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=11.1µM) |
| 15 |
ICV359 |
23.31 | 69.07% | 33.75% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=2.3µM); SARS(EC50=10µM) Vero E6 |
| 16 |
ICV307 |
23.28 | 66.52% | 35% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=24.8µM) |
| 17 |
ICV197 |
23.23 | 83.78% | 27.73% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=18.2µM) |
| 18 |
ICV352 |
23.1 | 69.29% | 33.33% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=1.3µM); SARS(EC50=5.2µM) Vero E6 |
| 19 |
ICV171 |
23.03 | 81.76% | 28.17% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=12.3µM) |
| 20 |
ICV176 |
22.81 | 77.3% | 29.51% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=0.31µM) |
