| 1 |
ICV15 |
24.38 | 63.91% | 38.15% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=57µM) |
| 2 |
ICV9 |
22.66 | 63.15% | 35.88% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=68µM) |
| 3 |
ICV10 |
22.4 | 65.36% | 34.27% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=63µM) |
| 4 |
ICV12 |
21.23 | 61.94% | 34.27% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=175µM) |
| 5 |
ICV398 |
20.73 | 79.91% | 25.95% |
virus: RNA-dependent RNA polymerase | P0DTD1 | polymerase extension experiments |
| 6 |
ICV339 |
20.61 | 70.89% | 29.08% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=0.15µM) |
| 7 |
ICV340 |
20.21 | 63.86% | 31.65% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=7µM) |
| 8 |
ICV197 |
20.17 | 74.4% | 27.11% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=18.2µM) |
| 9 |
ICV431 |
19.88 | 57.71% | 34.44% |
human: Histamine H1 receptor | P35367 | MERS(EC50=4.884µM) Vero E6; SARS(EC50=5.591µM) Vero E6 |
| 10 |
ICV13 |
19.81 | 58.8% | 33.7% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=135µM) |
| 11 |
ICV134 |
19.75 | 76.57% | 25.79% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=7.2µM) |
| 12 |
ICV396 |
19.71 | 79.33% | 24.84% |
virus: RNA-dependent RNA polymerase | P0DTD1 | SARS-CoV-2(EC50=95.96µM) Vero E6 |
| 13 |
ICV348 |
19.62 | 66.16% | 29.66% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=1.9µM) |
| 14 |
ICV8 |
19.59 | 56.25% | 34.83% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=108µM) |
| 15 |
ICV96 |
19.41 | 50.65% | 38.32% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=0.39µM) |
| 16 |
ICV399 |
19.39 | 77.56% | 25% |
virus: RNA-dependent RNA polymerase | P0DTD1 | polymerase extension experiments |
| 17 |
ICV243 |
19.38 | 74.22% | 26.11% |
virus: 3C-like protease | P0DTD1 | 82.55% inhibition ratio at 1mM |
| 18 |
ICV190 |
19.24 | 78.56% | 24.49% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=9.4µM) |
| 19 |
ICV338 |
19.14 | 67.46% | 28.37% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=0.49µM) |
| 20 |
ICV266 |
19.11 | 80.09% | 23.86% |
virus: 3C-like protease | P0DTD1 | SARS-CoV-2 3CL(IC50=1.82µM) |
