| 1 |
ICV146 |
21.05 | 63.62% | 33.09% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=32µM) |
| 2 |
ICV35 |
20.23 | 58.07% | 34.83% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=8.9µM); SARS 3CL(IC50=30.7µM) |
| 3 |
ICV25 |
18.93 | 60.77% | 31.15% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=7.4µM); SARS 3CL(IC50=5.8µM) |
| 4 |
ICV147 |
18.91 | 57.13% | 33.09% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=38.4µM) |
| 5 |
ICV373 |
18.36 | 57.42% | 31.97% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS 3CL(IC50=233.3µM); MERS PL(IC50=94.9µM) |
| 6 |
ICV32 |
18.31 | 57.67% | 31.74% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=8.9µM); SARS 3CL(IC50=11.7µM) |
| 7 |
ICV388 |
18.3 | 60.54% | 30.23% |
virus: Helicase | P0DTD1 | SARS(EC50=6µM) |
| 8 |
ICV370 |
18.19 | 49.89% | 36.46% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS 3CL(IC50=103.6µM); MERS 3CL(IC50=64.5µM); MERS PL(IC50=112.5µM) |
| 9 |
ICV30 |
18.1 | 58.6% | 30.89% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=10.1µM); SARS 3CL(IC50=20.2µM) |
| 10 |
ICV33 |
17.82 | 56.13% | 31.74% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=7.7µM); SARS 3CL(IC50=8.6µM) |
| 11 |
ICV28 |
17.71 | 56.96% | 31.1% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=44.7µM) |
| 12 |
ICV29 |
17.7 | 56.37% | 31.41% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=12.2µM); SARS 3CL(IC50=16.4µM) |
| 13 |
ICV148 |
17.52 | 53.13% | 32.97% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=72.3µM) |
| 14 |
ICV31 |
17.38 | 55.21% | 31.48% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=37.5µM) |
| 15 |
ICV403 |
17.3 | 56.88% | 30.41% |
virus: Envelope protein; Spike protein | QHD43418.1,P0DTC2 | FIPV(EC50=7.8µM) Black TN406HP |
| 16 |
ICV27 |
17.12 | 53.49% | 32.01% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=30.3µM); SARS 3CL(IC50=41.2µM) |
| 17 |
ICV37 |
16.92 | 58.01% | 29.17% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=15.7µM); SARS 3CL(IC50=9.7µM) |
| 18 |
ICV361 |
16.85 | 60.86% | 27.69% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=10.7µM); SARS 3CL(IC50=24.8µM) |
| 19 |
ICV34 |
16.72 | 51.59% | 32.4% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=9.6µM); SARS 3CL(IC50=18.7µM) |
| 20 |
ICV393 |
16.7 | 60.13% | 27.78% |
virus: Helicase | P0DTD1 | SARS nsP13 ATPase activity(IC50=2.71µM) |
