| 1 |
ICV392 |
22.89 | 61.4% | 37.28% |
virus: Helicase | P0DTD1 | SARS Helicase(IC50=5.4µM) |
| 2 |
ICV284 |
21.91 | 68.26% | 32.09% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=10.4µM) |
| 3 |
ICV440 |
21.56 | 59.84% | 36.02% |
human: Synaptic Vesicular amine transporter | Q05940 | SARS(EC50=3.4µM) Vero E6 |
| 4 |
ICV72 |
21.47 | 69.4% | 30.94% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=2.5µM) |
| 5 |
ICV373 |
20.81 | 61.77% | 33.69% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS 3CL(IC50=233.3µM); MERS PL(IC50=94.9µM) |
| 6 |
ICV285 |
20.46 | 63% | 32.47% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=13.9µM) |
| 7 |
ICV282 |
20.25 | 62.37% | 32.46% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=12.7µM) |
| 8 |
ICV428 |
20.13 | 64.37% | 31.27% |
human: Eukaryotic initiation factor 4A-I | P60842 | MERS(EC50=3nM) MRC-5 cell; HCoV-229E(EC50=1.3nM) MRC-5 cell |
| 9 |
ICV199 |
19.93 | 67.53% | 29.51% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=62.79µM) |
| 10 |
ICV280 |
19.54 | 62.65% | 31.18% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=9.2µM) |
| 11 |
ICV390 |
19.38 | 65.48% | 29.59% |
virus: Helicase | P0DTD1 | SARS Helicase(IC50=7µM) |
| 12 |
ICV202 |
19.31 | 66.65% | 28.97% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=90.72µM) |
| 13 |
ICV281 |
19.04 | 59.32% | 32.1% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=13.2µM) |
| 14 |
ICV200 |
18.82 | 63.28% | 29.75% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=101.38µM) |
| 15 |
ICV372 |
18.74 | 59.2% | 31.66% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS 3CL(IC50=84.8µM); MERS PL(IC50=88.5µM) |
| 16 |
ICV276 |
18.73 | 64.96% | 28.84% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=6.1µM) |
| 17 |
ICV403 |
18.59 | 54.06% | 34.39% |
virus: Envelope protein; Spike protein | QHD43418.1,P0DTC2 | FIPV(EC50=7.8µM) Black TN406HP |
| 18 |
ICV279 |
18.54 | 60.08% | 30.85% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=9.5µM) |
| 19 |
ICV374 |
18.45 | 60.08% | 30.71% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS 3CL(IC50=92.4µM); MERS 3CL(IC50=125.7µM); MERS PL(IC50=49.1µM) |
| 20 |
ICV442 |
18.38 | 56.91% | 32.3% |
human: 50S ribosomal protein L2 | P20276 | MERS(EC50=0.0718µM) Vero E6 |
