| 1 |
ICV189 |
25.76 | 57.81% | 44.57% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=0.03µM) |
| 2 |
ICV392 |
23.91 | 65.97% | 36.24% |
virus: Helicase | P0DTD1 | SARS Helicase(IC50=5.4µM) |
| 3 |
ICV175 |
23.31 | 57.44% | 40.57% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=0.03µM) |
| 4 |
ICV390 |
22.05 | 65.86% | 33.48% |
virus: Helicase | P0DTD1 | SARS Helicase(IC50=7µM) |
| 5 |
ICV617 |
21.74 | 56.96% | 38.16% |
human: Dihydroorotate dehydrogenase | Q02127 | SARS-CoV-2(EC50=1.96nM) Vero E6 |
| 6 |
ICV389 |
21.32 | 62.4% | 34.17% |
virus: Helicase | P0DTD1 | SARS Helicase(IC50=3µM) |
| 7 |
ICV176 |
21.24 | 56.02% | 37.91% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=0.31µM) |
| 8 |
ICV388 |
20.71 | 60.07% | 34.48% |
virus: Helicase | P0DTD1 | SARS(EC50=6µM) |
| 9 |
ICV310 |
20.51 | 69.43% | 29.55% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=2.7µM) |
| 10 |
ICV440 |
19.02 | 59.7% | 31.85% |
human: Synaptic Vesicular amine transporter | Q05940 | SARS(EC50=3.4µM) Vero E6 |
| 11 |
ICV64 |
18.62 | 55.85% | 33.33% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=24µM) |
| 12 |
ICV284 |
18.51 | 71.38% | 25.93% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=10.4µM) |
| 13 |
ICV188 |
18.46 | 60.07% | 30.73% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=13µM) |
| 14 |
ICV403 |
17.77 | 54.65% | 32.53% |
virus: Envelope protein; Spike protein | QHD43418.1,P0DTC2 | FIPV(EC50=7.8µM) Black TN406HP |
| 15 |
ICV276 |
17.74 | 62.4% | 28.43% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=6.1µM) |
| 16 |
ICV199 |
17.72 | 68.94% | 25.7% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=62.79µM) |
| 17 |
ICV437 |
17.7 | 53.11% | 33.33% |
human: Multiple kinases | NA | MERS(IC=2.31µM) Vero |
| 18 |
ICV119 |
17.63 | 62.6% | 28.17% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=7.5µM) |
| 19 |
ICV171 |
17.63 | 63.19% | 27.91% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(Ki=12.3µM) |
| 20 |
ICV206 |
17.63 | 64.36% | 27.4% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(EC50=23µM) |
