| 1 |
ICV31 |
32.19 | 73.23% | 43.96% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=37.5µM) |
| 2 |
ICV30 |
31.99 | 73.95% | 43.26% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=10.1µM); SARS 3CL(IC50=20.2µM) |
| 3 |
ICV32 |
30.72 | 69.11% | 44.44% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=8.9µM); SARS 3CL(IC50=11.7µM) |
| 4 |
ICV34 |
30.69 | 70.34% | 43.64% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=9.6µM); SARS 3CL(IC50=18.7µM) |
| 5 |
ICV27 |
30.43 | 67.7% | 44.94% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=30.3µM); SARS 3CL(IC50=41.2µM) |
| 6 |
ICV25 |
30.01 | 68.62% | 43.73% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=7.4µM); SARS 3CL(IC50=5.8µM) |
| 7 |
ICV29 |
29.64 | 67.06% | 44.2% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=12.2µM); SARS 3CL(IC50=16.4µM) |
| 8 |
ICV33 |
28.65 | 64.47% | 44.44% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=7.7µM); SARS 3CL(IC50=8.6µM) |
| 9 |
ICV26 |
28.63 | 65.48% | 43.73% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=7.3µM); SARS 3CL(IC50=6.0µM) |
| 10 |
ICV186 |
28.47 | 61.69% | 46.15% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=38.57µM) |
| 11 |
ICV28 |
27.51 | 64.2% | 42.86% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=44.7µM) |
| 12 |
ICV362 |
27.09 | 75.53% | 35.87% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=9.2µM); SARS 3CL(IC50=21.1µM) |
| 13 |
ICV35 |
26.42 | 61.13% | 43.21% |
virus: 3C-like protease | P0DTD1 | MERS 3CL(IC50=8.9µM); SARS 3CL(IC50=30.7µM) |
| 14 |
ICV361 |
23.31 | 69.06% | 33.76% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=10.7µM); SARS 3CL(IC50=24.8µM) |
| 15 |
ICV360 |
23.15 | 68.24% | 33.92% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=1.6µM); SARS 3CL(IC50=89.1µM) |
| 16 |
ICV363 |
22.84 | 68.84% | 33.18% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=8.8µM); SARS 3CL(IC50=38.7µM) |
| 17 |
ICV364 |
22.58 | 65.65% | 34.39% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=4.9µM); SARS 3CL(IC50=14.4µM) |
| 18 |
ICV297 |
22.33 | 68.44% | 32.63% |
virus: Papain-like protease | P0DTD1 | SARS PL(IC50=0.8µM) |
| 19 |
ICV365 |
21.76 | 69.02% | 31.53% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS PL(IC50=30µM); SARS 3CL(IC50=21.1µM) |
| 20 |
ICV203 |
21.62 | 51.01% | 42.39% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=41.39µM) |
