| 1 |
ICV134 |
19.45 | 68.09% | 28.57% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=7.2µM) |
| 2 |
ICV274 |
19.41 | 82.51% | 23.53% |
virus: Papain-like protease | P0DTD1 | MERS PL(IC50=20µM) |
| 3 |
ICV407 |
18.77 | 65.06% | 28.85% |
human: ACE2 | P59594 | SARS(EC50=3.1µM) 293T cell |
| 4 |
ICV414 |
15.73 | 69.65% | 22.58% |
human: Calpain | NA | SARS(EC50=2µM) Vero 76 |
| 5 |
ICV378 |
15.2 | 79.94% | 19.02% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS 3CL(IC50=116.3µM); MERS 3CL(IC50=35.3µM); MERS PL(IC50=206.6µM) |
| 6 |
ICV393 |
15.2 | 80.29% | 18.93% |
virus: Helicase | P0DTD1 | SARS nsP13 ATPase activity(IC50=2.71µM) |
| 7 |
ICV43 |
14.97 | 77.27% | 19.38% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=4.47µM) |
| 8 |
ICV379 |
14.96 | 79.02% | 18.93% |
virus: Papain-like protease; 3C-like protease | P0DTD1 | SARS 3CL(IC50=52.7µM); MERS 3CL(IC50=34.8µM) |
| 9 |
ICV394 |
14.83 | 80.31% | 18.47% |
virus: Helicase | P0DTD1 | SARS nsP13 ATPase activity(IC50=0.86µM) |
| 10 |
ICV162 |
14.55 | 71.25% | 20.42% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=6.1µM) |
| 11 |
ICV254 |
14.19 | 71.71% | 19.79% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=12.66µM) |
| 12 |
ICV258 |
14.18 | 73.22% | 19.37% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=11.83µM) |
| 13 |
ICV253 |
14.16 | 74.32% | 19.05% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=4.45µM) |
| 14 |
ICV260 |
14.08 | 71.91% | 19.59% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=9.91µM) |
| 15 |
ICV262 |
13.72 | 70.81% | 19.37% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=17.82µM) |
| 16 |
ICV247 |
13.68 | 69.86% | 19.58% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=76.74µM) |
| 17 |
ICV161 |
13.65 | 67.2% | 20.31% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=10.6µM) |
| 18 |
ICV252 |
13.46 | 68.97% | 19.52% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=51.33µM) |
| 19 |
ICV256 |
13.4 | 69.16% | 19.37% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=2.25µM) |
| 20 |
ICV76 |
13.35 | 54.13% | 24.66% |
virus: 3C-like protease | P0DTD1 | SARS 3CL(IC50=21µM) |
