1 | Dihydroorotate dehydrogenase | | -8.85 | Q02127 | Pocket1 | human | PDB | 25 |
2 | Spike protein | Open | -8.17 | QHD43416.1 | Pocket5 | SARS-CoV-2 | Swiss-model | 2 |
3 | RNA-dependent RNA polymerase | +RNA & +Mg | -8.13 | QHD43415.1 | Pocket6 | SARS-CoV-2 | PDB | 33 |
4 | ADP ribose phosphatase | Monomer | -8.06 | QHD43415.1 | Pocket1 | SARS-CoV-2 | PDB | 18 |
5 | ADP ribose phosphatase | Dimer | -8.05 | QHD43415.1 | Pocket2 | SARS-CoV-2 | PDB | 18 |
6 | cGMP-specific 3',5'-cyclic phosphodiesterase | | -7.94 | O76074 | Pocket1 | human | PDB | 39 |
7 | RAC-alpha serine/threonine-protein kinase | | -7.8 | P31749 | Pocket1 | human | PDB | 39 |
8 | Mitogen-activated protein kinase 9/c-Jun N-terminal kinase 2 | | -7.79 | P45984 | Pocket1 | human | Swiss-model | 23 |
9 | Complement Component 5 | Monomer | -7.72 | P01031 | Pocket1 | human | PDB | 22 |
10 | ORF1ab polyprotein 819-2763 Papain-like proteinase | Dimer | -7.69 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 29 |
11 | Tyrosine-protein kinase ABL2 | | -7.59 | P42684 | Pocket1 | human | PDB | 28 |
12 | ORF1ab polyprotein 5926-6452 Guanine-N7 methyltransferase | | -7.56 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 31 |
13 | Spike protein | Open | -7.53 | QHD43416.1 | Pocket6 | SARS-CoV-2 | PDB | 23 |
14 | Caveolin-2 | | -7.42 | P51636 | Pocket1 | human | Robetta | 28 |
15 | ORF1ab 5325-5925 Helicase | Dimer | -7.39 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 17 |
16 | Complement Component 5 | Dimer | -7.39 | P01031 | Pocket1 | human | PDB | 26 |
17 | ORF1ab polyprotein 6453-6798 Uridylate-specific endoribonuclease | | -7.38 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 27 |
18 | ORF1ab polyprotein 819-2763 Papain-like proteinase | Monomer | -7.22 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 27 |
19 | Heterogeneous nuclear ribonucleoprotein A1 | | -7.2 | P09651 | Pocket1 | human | PDB | 29 |
20 | Non-structural protein 4 | | -7.2 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Robetta | 33 |
21 | Non-structural protein 2 | | -7.19 | QHD43415.1 | Pocket4 | SARS-CoV-2 | Robetta | 40 |
22 | Mitogen-activated protein kinase 10/c-Jun N-terminal kinase 3 | | -7.05 | P53779 | Pocket1 | human | PDB | 30 |
23 | Mitogen-activated protein kinase 8/c-Jun N-terminal kinase 1 | | -7.04 | P45983 | Pocket1 | human | Swiss-model | 38 |
24 | Non-structural protein 6 | | -7.04 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Robetta | 23 |
25 | RAC-beta serine/threonine-protein kinase | | -7.04 | P31751 | Pocket1 | human | PDB | 32 |
26 | Envelope protein | Pentamer | -6.99 | QHD43418.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 25 |
27 | Complement Component 3 | | -6.99 | P01024 | Pocket15 | human | PDB | 10 |
28 | ORF1ab polyprotein 4393-5324 RNA-dependent RNA polymerase | +Mg | -6.96 | QHD43415.1 | Pocket3 | SARS-CoV-2 | Swiss-model | 24 |
29 | ORF1ab polyprotein 4393-5324 RNA-dependent RNA polymerase | | -6.96 | QHD43415.1 | Pocket3 | SARS-CoV-2 | Swiss-model | 24 |
30 | ORF1ab polyprotein 5325-5925 Helicase | Monomer | -6.96 | QHD43415.1 | Pocket2 | SARS-CoV-2 | Swiss-model | 38 |
31 | Uridylate-specific endoribonuclease | Dimer | -6.93 | QHD43415.1 | Pocket3 | SARS-CoV-2 | PDB | 29 |
32 | SARS-COV-2 chimeric receptor-binding domain+Angiotensin converting enzyme 2 | | -6.93 | / | Pocket1 | human | PDB | 26 |
33 | RNA-dependent RNA polymerase | Only Nsp12 & MD | -6.93 | P0DTD1 | Pocket3 | SARS-CoV-2 | Molecular Dynamics | 29 |
34 | Uridylate-specific endoribonuclease | Monomer | -6.91 | QHD43415.1 | Pocket1 | SARS-CoV-2 | PDB | 31 |
35 | 3C-like proteinase | Monomer | -6.9 | QHD43415.1 | Pocket2 | SARS-CoV-2 | PDB | 14 |
36 | Nucleocapsid phosphoprotein | N terminal | -6.89 | QHD43423.2 | Pocket1 | SARS-CoV-2 | Swiss-model | 34 |
37 | Spike protein | Closed | -6.87 | QHD43416.1 | Pocket2 | SARS-CoV-2 | PDB | 36 |
38 | Eukaryotic initiation factor 4A-I | | -6.85 | P60842 | Pocket3 | human | PDB | 30 |
39 | Disintegrin and metalloproteinase domain-containing protein 17 | | -6.8 | P78536 | Pocket1 | human | Swiss-model | 37 |
40 | ORF1ab polyprotein 6799-7096 2'-O-methyltransferase | | -6.77 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 18 |
41 | Calnexin | | -6.75 | P27824 | Pocket4 | human | Swiss-model | 17 |
42 | Nucleocapsid phosphoprotein | N terminal & Tetramer | -6.74 | QHD43423.2 | Pocket1 | SARS-CoV-2 | PDB | 40 |
43 | Disintegrin and metalloproteinase domain-containing protein 17 | +Zn | -6.7 | P78536 | Pocket1 | human | | 43 |
44 | Non-structural protein 7 + Non-structural protein 8 | Complex | -6.7 | P0DTC1 | Pocket1 | SARS-CoV-2 | PDB | 20 |
45 | 3C-like proteinase | MD | -6.69 | QHD43415.1 | Pocket2 | SARS-CoV-2 | Swiss-model | 28 |
46 | Glycogen synthase kinase-3 beta | | -6.69 | P49841 | Pocket1 | human | PDB | 38 |
47 | Nucleocapsid phosphoprotein | C terminal | -6.68 | QHD43423.2 | Pocket1 | SARS-CoV-2 | Swiss-model | 29 |
48 | Furin | | -6.64 | P09958 | Pocket1 | human | PDB | 35 |
49 | Angiotensin converting enzyme 2 | | -6.61 | P59594 | Pocket1 | human | PDB | 34 |
50 | Papain-like proteinase | Trimer | -6.6 | QHD43415.1 | Pocket3 | SARS-CoV-2 | PDB | 40 |
51 | ORF1ab polyprotein 3264-3569 3C-like proteinase | Monomer | -6.59 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 27 |
52 | 3C-like proteinase | MD | -6.59 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 22 |
53 | 3C-like proteinase | Dimer | -6.58 | QHD43415.1 | Pocket2 | SARS-CoV-2 | PDB | 30 |
54 | Calnexin | +Ca | -6.58 | P27823 | Pocket4 | human | | 21 |
55 | Spike protein | Closed | -6.57 | QHD43416.1 | Pocket5 | SARS-CoV-2 | Swiss-model | 19 |
56 | Nucleocapsid phosphoprotein | C terminal & Monomer | -6.54 | P0DTC9 | Pocket1 | SARS-CoV-2 | PDB | 36 |
57 | Transmembrane protease serine 2 | | -6.53 | O15393 | Pocket3 | human | Robetta | 24 |
58 | Papain-like protease | Monomer | -6.52 | QHD43415.1 | Pocket5 | SARS-CoV-2 | PDB | 21 |
59 | ORF1ab polyprotein 3264-3569 3C-like proteinase | Dimer | -6.51 | QHD43415.1 | Pocket5 | SARS-CoV-2 | Swiss-model | 32 |
60 | Spike protein S2 subunit | | -6.46 | / | Pocket2 | SARS-CoV-2 | PDB | 17 |
61 | 3C-like proteinase | MD | -6.46 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 25 |
62 | Nucleocapsid phosphoprotein | C terminal & Dimer | -6.45 | P0DTC9 | Pocket1 | SARS-CoV-2 | PDB | 29 |
63 | RNA-dependent RNA polymerase | | -6.44 | QHD43415.1 | Pocket10 | SARS-CoV-2 | PDB | 7 |
64 | 2'-O-Methyltransferase | | -6.42 | P0DTD1 | Pocket1 | SARS-CoV-2 | PDB | 34 |
65 | AP2-associated protein kinase 1 | | -6.42 | Q2M2I8 | Pocket5 | human | PDB | 25 |
66 | Non-structural protein 10 | | -6.39 | P0DTC1 | Pocket1 | SARS-CoV-2 | PDB | 29 |
67 | 3C-like proteinase | MD | -6.38 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 26 |
68 | Cyclophilin A | | -6.32 | P62937 | Pocket1 | human | PDB | 31 |
69 | Spike protein-heptad repeat 1 | | -6.3 | QHD43416.1 | Pocket3 | SARS-CoV-2 | Swiss-model | 27 |
70 | Non-structural protein 9 | Dimer | -6.29 | QHD43415.1 | Pocket4 | SARS-CoV-2 | PDB | 9 |
71 | Non-structural protein 9 | Monomer | -6.27 | QHD43415.1 | Pocket1 | SARS-CoV-2 | PDB | 19 |
72 | ORF1ab polyprotein 4141-4253 Non-structural protein 9 | Monomer | -6.23 | QHD43415.1 | Pocket2 | SARS-CoV-2 | Swiss-model | 25 |
73 | Cathepsin L | | -6.18 | P07711 | Pocket2 | human | PDB | 26 |
74 | ORF1ab polyprotein 4254-4392 Non-structural protein 10 | | -6.06 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 33 |
75 | ORF1ab polyprotein 3943-4140 Non-structural protein 8 | | -6.02 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 27 |
76 | RAC-gamma serine/threonine-protein kinase | | -5.97 | Q9Y243 | Pocket1 | human | PDB | 27 |
77 | ORF1ab polyprotein 4141-4253 Non-structural protein 9 | Dimer | -5.73 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 19 |
78 | C type lectin domain family 4 member M | | -5.65 | Q9H2X3 | Pocket1 | human | PDB | 20 |
79 | ORF1ab polyprotein 3860-3942 Non-structural protein 7 | | -5.38 | QHD43415.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 34 |
80 | ORF7a protein | | -5.38 | QHD43421.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 17 |
81 | ORF7a protein | | -5.36 | P0DTC7 | Pocket1 | SARS-CoV-2 | PDB | 32 |
82 | Nucleocapsid phosphoprotein | N terminal & Monomer | -5.35 | QHD43423.2 | Pocket1 | SARS-CoV-2 | PDB | 42 |
83 | ORF1ab polyprotein 1-180 Host translation inhibitor nsp1 | | -5.1 | QHD43415.1 | Pocket3 | SARS-CoV-2 | Swiss-model | 35 |
84 | Envelope protein | Monomer | -5.09 | QHD43418.1 | Pocket1 | SARS-CoV-2 | Swiss-model | 29 |