Target Detail

ORF1ab polyprotein 5926-6452 Guanine-N7 methyltransferase

Abbreviation: N7-MTase

Uniprot id / Protein id:QHD43415.1

Organism:SARS-CoV-2

Mechanism:N7-MTase is a bifunctional enzyme able to methylate the viral RNA cap and excise erroneous mutagenic nucleotides.

Reference (PMID or DOI):22635272, 29279395

Model Source:Swiss-model

Template PDB_ID:5nfy

Sequence Identity:94.88%

Pockets:There are 12 pockets in ORF1ab polyprotein 5926-6452 Guanine-N7 methyltransferase.
pocket 1:

pocket 2:

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