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CoViProteins
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2019-nCoV
Target Detail
ORF1ab polyprotein 5926-6452 Guanine-N7 methyltransferase
Abbreviation: N7-MTase
Uniprot id / Protein id:
QHD43415.1
Organism:
SARS-CoV-2
Mechanism:
N7-MTase is a bifunctional enzyme able to methylate the viral RNA cap and excise erroneous mutagenic nucleotides.
Reference (PMID or DOI):
22635272
,
29279395
Model Source:
Swiss-model
Template PDB_ID:
5nfy
Sequence Identity:
94.88%
Pockets:
There are 12 pockets in ORF1ab polyprotein 5926-6452 Guanine-N7 methyltransferase.
pocket 1:
pocket 2:
pocket 3:
pocket 4:
pocket 5:
pocket 6:
pocket 7:
pocket 8:
pocket 9:
pocket 10:
pocket 11:
pocket 12:
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