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CoViProteins
2019-nCoV
CoViLigands
Introduction
2019-nCoV
Target Detail
Sigma-1 receptor
Abbreviation: Sigma-1 receptor
Uniprot id / Protein id:
Q99720
Organism:
human
Mechanism:
Knockout and knockdown of sigma-1 receptor caused robust reductions in SARS-CoV-2 replication, which indicates that the sigma-1 receptor is a potential therapeutic target for SARS-CoV-2 replication.
Reference (PMID or DOI):
33403480
Model Source:
PDB
Template PDB_ID:
5hk1
Pockets:
There are 3 pockets in Sigma-1 receptor.
pocket 1:
pocket 2:
pocket 3:
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