Target Detail

Sigma-1 receptor

Abbreviation: Sigma-1 receptor

Uniprot id / Protein id:Q99720

Organism:human

Mechanism:Knockout and knockdown of sigma-1 receptor caused robust reductions in SARS-CoV-2 replication, which indicates that the sigma-1 receptor is a potential therapeutic target for SARS-CoV-2 replication.

Reference (PMID or DOI):33403480

Model Source:PDB

Template PDB_ID:5hk1

Pockets:There are 3 pockets in Sigma-1 receptor.
pocket 1:

pocket 2:

pocket 3:

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