Target Detail

Disintegrin and metalloproteinase domain-containing protein 17

Abbreviation: ADAM17/TACE

Uniprot id / Protein id:P78536

Organism:human

Mechanism:ADAM17 is required in the proteolytic processing of ACE2.

Reference (PMID or DOI):24227843

Model Source:Swiss-model

Template PDB_ID:2i47

Sequence Identity:99.21%

Pockets:There are 5 pockets in Disintegrin and metalloproteinase domain-containing protein 17.
pocket 1:

pocket 2:

pocket 3:

pocket 4:

pocket 5:

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