Target Detail

ORF1ab polyprotein 1-180 Host translation inhibitor nsp1

Abbreviation: Nsp1

Uniprot id / Protein id:QHD43415.1

Organism:SARS-CoV-2

Mechanism:Nsp1 can facilitate efficient viral gene expression in infected cells and evasion from host immune response by suppressing host gene expression.

Reference (PMID or DOI):23035226, 22855488

Model Source:Swiss-model

Template PDB_ID:2hsx

Sequence Identity:86.09%

Pockets:There are 3 pockets in ORF1ab polyprotein 1-180 Host translation inhibitor nsp1.
pocket 1:

pocket 2:

pocket 3:

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