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CoViProteins
2019-nCoV
CoViLigands
Introduction
2019-nCoV
Target Detail
ORF1ab polyprotein 1-180 Host translation inhibitor nsp1
Abbreviation: Nsp1
Uniprot id / Protein id:
QHD43415.1
Organism:
SARS-CoV-2
Mechanism:
Nsp1 can facilitate efficient viral gene expression in infected cells and evasion from host immune response by suppressing host gene expression.
Reference (PMID or DOI):
23035226
,
22855488
Model Source:
Swiss-model
Template PDB_ID:
2hsx
Sequence Identity:
86.09%
Pockets:
There are 3 pockets in ORF1ab polyprotein 1-180 Host translation inhibitor nsp1.
pocket 1:
pocket 2:
pocket 3:
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