Target Detail

ORF1ab polyprotein 6453-6798 Uridylate-specific endoribonuclease

Abbreviation: NendoU

Uniprot id / Protein id:QHD43415.1

Organism:SARS-CoV-2

Mechanism:NendoU is a Mn2+-dependent, uridylate-specific enzyme, which leaves 2'-3'-cyclic phosphates 5' to the cleaved bond.

Reference (PMID or DOI):16882730

Model Source:Swiss-model

Template PDB_ID:2h85

Sequence Identity:88.12%

Pockets:There are 7 pockets in ORF1ab polyprotein 6453-6798 Uridylate-specific endoribonuclease.
pocket 1:

pocket 2:

pocket 3:

pocket 4:

pocket 5:

pocket 6:

pocket 7:

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