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D3AI-Spike
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CoViProteins
2019-nCoV
CoViLigands
Introduction
2019-nCoV
Target Detail
Complement Component 3
Abbreviation: C3
Uniprot id / Protein id:
P01024
Organism:
human
Mechanism:
Activation of C3 can exacerbate SARS-CoV-associated disease. And C3 inhibition may alleviate the inflammatory lung complications of SARS-CoV-2 infection.
Reference (PMID or DOI):
30301856
,
32327719
Model Source:
PDB
Template PDB_ID:
2a73
Pockets:
There are 26 pockets in Complement Component 3.
pocket 1:
pocket 2:
pocket 3:
pocket 4:
pocket 5:
pocket 6:
pocket 7:
pocket 8:
pocket 9:
pocket 10:
pocket 11:
pocket 12:
pocket 13:
pocket 14:
pocket 15:
pocket 16:
pocket 17:
pocket 18:
pocket 19:
pocket 20:
pocket 21:
pocket 22:
pocket 23:
pocket 24:
pocket 25:
pocket 26:
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