Target Detail

Complement Component 3

Abbreviation: C3

Uniprot id / Protein id:P01024

Organism:human

Mechanism:Activation of C3 can exacerbate SARS-CoV-associated disease. And C3 inhibition may alleviate the inflammatory lung complications of SARS-CoV-2 infection. 

Reference (PMID or DOI):30301856, 32327719

Model Source:PDB

Template PDB_ID:2a73

Pockets:There are 26 pockets in Complement Component 3.
pocket 1:

pocket 2:

pocket 3:

pocket 4:

pocket 5:

pocket 6:

pocket 7:

pocket 8:

pocket 9:

pocket 10:

pocket 11:

pocket 12:

pocket 13:

pocket 14:

pocket 15:

pocket 16:

pocket 17:

pocket 18:

pocket 19:

pocket 20:

pocket 21:

pocket 22:

pocket 23:

pocket 24:

pocket 25:

pocket 26:

This site has been visited 3723572 times since Feb 2020.